Human autoantibodies underlying infectious diseases

A Puel, P Bastard, J Bustamante… - Journal of Experimental …, 2022 - rupress.org
The vast interindividual clinical variability observed in any microbial infection—ranging from
silent infection to lethal disease—is increasingly being explained by human genetic and …

An overlooked and underrated endemic mycosis—Talaromycosis and the pathogenic fungus Talaromyces marneffei

F Wang, RH Han, S Chen - Clinical Microbiology Reviews, 2023 - Am Soc Microbiol
Talaromycosis is an invasive mycosis endemic in tropical and subtropical Asia and is
caused by the pathogenic fungus Talaromyces marneffei. Approximately 17,300 cases of T …

Immunity to invasive fungal diseases

A Casadevall - Annual review of immunology, 2022 - annualreviews.org
Invasive fungal diseases are rare in individuals with intact immunity. This, together with the
fact that there are only a few species that account for most mycotic diseases, implies a …

Anti–Interleukin-23 Autoantibodies in Adult-Onset Immunodeficiency

A Cheng, A Kashyap, H Salvator… - … England Journal of …, 2024 - Mass Medical Soc
Background Autoantibodies against interleukin-12 (anti–interleukin-12) are often identified
in patients with thymoma, but opportunistic infections develop in only some of these patients …

Race and ethnicity: Risk factors for fungal infections?

JD Jenks, CI Aneke, MM Al-Obaidi, M Egger… - PLoS …, 2023 - journals.plos.org
Racial and ethnic identities, largely understood as social rather than biologic constructs,
may impact risk for acquiring infectious diseases, including fungal infections. Risk factors …

Anti-interferon-γ autoantibody-associated immunodeficiency

HP Shih, JY Ding, CF Yeh, CY Chi, CL Ku - Current Opinion in Immunology, 2021 - Elsevier
Anticytokine autoantibodies are an emerging disease etiology, through the disturbance of
physiological functions of cognate cytokines. Anti-interferon (IFN)-γ autoantibodies (AIGAs) …

Talaromyces marneffei Infection: Virulence, Intracellular Lifestyle and Host Defense Mechanisms

K Pruksaphon, JD Nosanchuk, K Ratanabanangkoon… - Journal of Fungi, 2022 - mdpi.com
Talaromycosis (Penicilliosis) is an opportunistic mycosis caused by the thermally dimorphic
fungus Talaromyces (Penicillium) marneffei. Similar to other major causes of systemic …

Interferon-γ and infectious diseases: Lessons and prospects

JL Casanova, JD MacMicking, CF Nathan - Science, 2024 - science.org
Infectious diseases continue to claim many lives. Prevention of morbidity and mortality from
these diseases would benefit not just from new medicines and vaccines but also from a …

Mycobacterial diseases in patients with inborn errors of immunity

S Boisson-Dupuis, J Bustamante - Current opinion in immunology, 2021 - Elsevier
Clinical disease caused by the agent of tuberculosis, Mycobacterium tuberculosis, and by
less virulent mycobacteria, such as bacillus Calmette-Guérin (BCG) vaccines and …

Rapid diagnosis of Talaromyces marneffei infection by metagenomic next-generation sequencing technology in a Chinese cohort of inborn errors of immunity

L Liu, B Sun, W Ying, D Liu, Y Wang, J Sun… - Frontiers in cellular …, 2022 - frontiersin.org
Talaromyces marneffei (T. marneffei) is an opportunistic pathogen. Patients with inborn
errors of immunity (IEI) have been increasingly diagnosed with T. marneffei in recent years …