Advances in the diagnosis and treatment of non-alcoholic fatty liver disease

X Yin, X Guo, Z Liu, J Wang - International Journal of Molecular Sciences, 2023 - mdpi.com
Non-alcoholic fatty liver disease (NAFLD) is the most prevalent chronic liver disease that
affects approximately one-quarter of the global adult population, posing a significant threat …

[HTML][HTML] Peroxisome proliferator-activated receptors: A key link between lipid metabolism and cancer progression

Y Li, Y Pan, X Zhao, S Wu, F Li, Y Wang, B Liu… - Clinical Nutrition, 2024 - Elsevier
Lipids represent the essential components of membranes, serve as fuels for high-energy
processes, and play crucial roles in signaling and cellular function. One of the key hallmarks …

[HTML][HTML] Fatty acids and evolving roles of their proteins in neurological, cardiovascular disorders and cancers

R Mallick, S Basak, AK Duttaroy - Progress in lipid research, 2021 - Elsevier
The dysregulation of fat metabolism is involved in various disorders, including
neurodegenerative, cardiovascular, and cancers. The uptake of long-chain fatty acids …

Emerging hallmarks of metabolic reprogramming in prostate cancer

F Lasorsa, NA di Meo, M Rutigliano, M Ferro… - International Journal of …, 2023 - mdpi.com
Prostate cancer (PCa) is the most common male malignancy and the fifth leading cause of
cancer death in men worldwide. Prostate cancer cells are characterized by a hybrid …

Metabolic heterogeneity in cancer

M Demicco, XZ Liu, K Leithner, SM Fendt - Nature Metabolism, 2024 - nature.com
Cancer cells rewire their metabolism to survive during cancer progression. In this context,
tumour metabolic heterogeneity arises and develops in response to diverse environmental …

The Multifunctional Family of Mammalian Fatty Acid–Binding Proteins

J Storch, B Corsico - Annual review of nutrition, 2023 - annualreviews.org
Fatty acid–binding proteins (FABPs) are small lipid-binding proteins abundantly expressed
in tissues that are highly active in fatty acid (FA) metabolism. Ten mammalian FABPs have …

Prostate cancer progression: as a matter of fats

N Scaglia, YR Frontini-López, G Zadra - Frontiers in Oncology, 2021 - frontiersin.org
Advanced prostate cancer (PCa) represents the fifth cause of cancer death worldwide.
Although survival has improved with second-generation androgen signaling and Parp …

Fatty acid oxidation: driver of lymph node metastasis

M Li, H Xian, YJ Tang, X Liang, Y Tang - Cancer Cell International, 2021 - Springer
Fatty acid oxidation (FAO) is the emerging hallmark of cancer metabolism because certain
tumor cells preferentially utilize fatty acids for energy. Lymph node metastasis, the most …

Fatty acid metabolism reprogramming in advanced prostate cancer

H Xu, Y Chen, M Gu, C Liu, Q Chen, M Zhan, Z Wang - Metabolites, 2021 - mdpi.com
Prostate cancer (PCa) is a carcinoma in which fatty acids are abundant. Fatty acid
metabolism is rewired during PCa development. Although PCa can be treated with hormone …

Peroxisome proliferator-activated receptors and the hallmarks of cancer

N Wagner, KD Wagner - Cells, 2022 - mdpi.com
Peroxisome proliferator-activated receptors (PPARs) function as nuclear transcription factors
upon the binding of physiological or pharmacological ligands and heterodimerization with …