[HTML][HTML] Translational issues in cochlear synaptopathy

AE Hickox, E Larsen, MG Heinz, L Shinobu, JP Whitton - Hearing research, 2017 - Elsevier
Understanding the biology of the previously underappreciated sensitivity of cochlear
synapses to noise insult, and its clinical consequences, is becoming a mission for a growing …

[HTML][HTML] The hearing hippocampus

AJ Billig, M Lad, W Sedley, TD Griffiths - Progress in neurobiology, 2022 - Elsevier
The hippocampus has a well-established role in spatial and episodic memory but a broader
function has been proposed including aspects of perception and relational processing …

The rat animal model for noise-induced hearing loss

CD Escabi, MD Frye, M Trevino… - The Journal of the …, 2019 - pubs.aip.org
Rats make excellent models for the study of medical, biological, genetic, and behavioral
phenomena given their adaptability, robustness, survivability, and intelligence. The rat's …

Systemic health effects of noise exposure

L Yang, DE Gutierrez, OW Guthrie - Journal of Toxicology and …, 2024 - Taylor & Francis
Noise, any unwanted sound, is pervasive and impacts large populations worldwide.
Investigators suggested that noise exposure not only induces auditory damage but also …

Noise exposure and oxidative balance in auditory and extra-auditory structures in adult and developing animals. Pharmacological approaches aimed to minimize its …

SJ Molina, M Miceli, LR Guelman - Pharmacological Research, 2016 - Elsevier
Noise coming from urban traffic, household appliances or discotheques might be as
hazardous to the health of exposed people as occupational noise, because may likewise …

Repeated moderate sound exposure causes accumulated trauma to cochlear ribbon synapses in mice

Y Luo, T Qu, Q Song, Y Qi, S Yu, S Gong, K Liu, X Jiang - Neuroscience, 2020 - Elsevier
Repeated induction of a temporary threshold shift (TTS) may result in a permanent threshold
shift (PTS) and is thought to be associated with early onset of age-related hearing loss …

Noise‐induced hippocampal oxidative imbalance and aminoacidergic neurotransmitters alterations in developing male rats: Influence of enriched environment during …

SJ Molina, GE Buján… - Developmental …, 2021 - Wiley Online Library
Living in big cities might involuntarily expose people to high levels of noise causing auditory
and/or extra‐auditory impairments, including adverse effects on central nervous system …

Effects of early noise exposure on hippocampal-dependent behaviors during adolescence in male rats: influence of different housing conditions

SJ Molina, ÁE Lietti, CS Carreira Caro, GE Buján… - Animal Cognition, 2022 - Springer
Central nervous system (CNS) development is a very complex process that can be altered
by environmental stimuli such as noise, which can generate long-term auditory and/or extra …

Assessment of hippocampal-related behavioral changes in adolescent rats of both sexes following voluntary intermittent ethanol intake and noise exposure: a putative …

GE Buján, L D'Alessio, HA Serra, LR Guelman… - Neurotoxicity …, 2024 - Springer
Ethanol (EtOH) intake and noise exposure are particularly concerning among human
adolescents because the potential to harm brain. Unfortunately, putative underlying …

Noise exposure of immature rats can induce different age-dependent extra-auditory alterations that can be partially restored by rearing animals in an enriched …

SJ Molina, F Capani, LR Guelman - Brain research, 2016 - Elsevier
It has been previously shown that different extra-auditory alterations can be induced in
animals exposed to noise at 15 days. However, data regarding exposure of younger …