Advanced medicated wound dressings fabricated by electrospinning and electrospraying
were prepared for the eradication of topical bacterial infections potentially applied in the …

Overexpression of efflux pumps is one of the major determinants of resistance in bacteria.
Streptomyces species harbor a large array of efflux pumps that are transcriptionally silenced …

The discovery of molecules that could shorten the treatment period of tuberculosis (TB)
holds the promise of improving the current regimen. Polyamines are organic polycationic …

The nontuberculous mycobacteria (NTM) have recently emerged as important bacterial
pathogens of both animals and humans. Of particular, concern is the high level of …

Copper (Cu) ions are critical in controlling bacterial infections, and successful pathogens
like Mycobacterium tuberculosis (Mtb) possess multiple Cu resistance mechanisms. We …

The current anti-TB treatment consists of a prolonged multi-drug therapy. Interventional
strategies are required to reduce the chemotherapeutic load. In this regard, we have …

The observations that the innate immune system employs copper to eliminate bacterial
infection and that resistance to copper enhances virulence of Mycobacterium tuberculosis …

Glutathione-S-transferases (GST) enzymes detoxify xenobiotics and are implicated in
response to anticancer therapy. This study evaluated the association of GST theta 1 …

The prevalence of Mycobacterium avium complex-pulmonary disease (MAC-PD) has
become a growing concern worldwide, and current treatments involving macrolides …

The study was designed to assess whether plant extracts/phytochemical (D-Pinitol)
synergistically combine with antituberculosis drugs and act on Mycobacterium smegmatis …