Cellular states are determined by differential expression of the cell's proteins. The
relationship between protein and mRNA expression levels informs about the combined …

Enolase is a glycolytic enzyme, which catalyzes the inter-conversion of 2-phosphoglycerate
to phosphoenolpyruvate. Altered expression of this enzyme is frequently observed in cancer …

The molecular mechanisms underlying transcriptional regulation in apicomplexan parasites
remain poorly understood. Recently, the Apicomplexan AP2 (ApiAP2) family of DNA binding …

Background The human malaria parasite Plasmodium falciparum has a complex and multi-
stage life cycle that requires extensive and precise gene regulation to allow invasion and …

During asexual intraerythrocytic development, Plasmodium falciparum diverges from the
paradigm of the eukaryotic cell cycles by undergoing multiple rounds of DNA replication and …

Studies of the Plasmodium falciparum transcriptome have shown that the tightly controlled
progression of the parasite through the intra-erythrocytic developmental cycle (IDC) is …

Background In eukaryotic organisms, gene expression is regulated at multiple levels during
the processes of transcription and translation. The absence of a tight regulatory network for …

In eukaryotic organisms, noncoding RNAs (ncRNAs) have been implicated as important
regulators of multifaceted biological processes, including transcriptional, posttranscriptional …

Background Gene expression is controlled at multiple levels, including transcription,
stability, translation, and degradation. Over the years, it has become apparent that …

Malaria pathogenesis results from the asexual replication of Plasmodium falciparum within
human red blood cells, which relies on a precisely timed cascade of gene expression over a …