Structural information can help engineer enzymes. Usually, specific amino acids in particular
regions are targeted for functional reconstruction to enhance the catalytic performance …

Aliphatic α, ω‐dicarboxylic acids (DCAs) are a class of useful chemicals that are currently
produced by energy-intensive, multistage chemical oxidations that are hazardous to the …

δ-Aminolevulinic acid (1), represents a non-proteinogenic amino acid with a five-carbon
structure, serving as the primary precursor for the biosynthesis of tetrapyrrole molecules …

Abstract L‐Homophenylalanine (L‐HPA) is a vital building block for the synthesis of
numerous chiral drugs. However, the high cost of starting materials limits the industrial …

Threonine deaminase (TD, EC 4.3. 1.19) mediates α, β-elimination (deamination), which has
untapped potential in the synthesis of unnatural α-keto acids. However, the narrow substrate …

Aldehydes are attractive chemical targets both as end products in the flavors and fragrances
industry and as synthetic intermediates due to their propensity for C–C bond formation …

Alkenes are excellent starting materials for organic synthesis due to the versatile reactivity of
CC bonds and the easy availability of many unfunctionalised alkenes. Direct regio-and/or …

1, 6-Hexanediol (HDO) is an important precursor in the polymer industry. The current
industrial route to produce HDO involves energy intensive and hazardous multistage (four …

Aliphatic α, ω‐diamines (DAs) are important monomer precursors that are industrially
produced by energy‐intensive, multistage chemical reactions that are harmful to the …

The development of mild, efficient, and enantioselective methods for preparing chiral
building blocks from simple, renewable carbon units has been a long‐term goal of the …