Genomic surveillance for antimicrobial resistance—a One Health perspective

SP Djordjevic, VM Jarocki, T Seemann… - Nature Reviews …, 2024 - nature.com
Antimicrobial resistance (AMR)—the ability of microorganisms to adapt and survive under
diverse chemical selection pressures—is influenced by complex interactions between …

[HTML][HTML] Klebsiella pneumoniae as a key trafficker of drug resistance genes from environmental to clinically important bacteria

KL Wyres, KE Holt - Current opinion in microbiology, 2018 - Elsevier
Klebsiella pneumoniae is an opportunistic bacterial pathogen known for its high frequency
and diversity of antimicrobial resistance (AMR) genes. In addition to being a significant …

OXA-48-Like β-Lactamases: global epidemiology, treatment options, and development pipeline

SE Boyd, A Holmes, R Peck… - Antimicrobial agents …, 2022 - Am Soc Microbiol
Modern medicine is threatened by the rising tide of antimicrobial resistance, especially
among Gram-negative bacteria, where resistance to β-lactams is most often mediated by β …

[HTML][HTML] The role of the natural aquatic environment in the dissemination of extended spectrum beta-lactamase and carbapenemase encoding genes: A scoping …

B Hooban, A Joyce, K Fitzhenry, C Chique, D Morris - Water Research, 2020 - Elsevier
The natural aquatic environment is a significant contributor to the development and
circulation of clinically significant antibiotic resistance genes (ARGs). The potential for the …

[HTML][HTML] Monitoring of hospital sewage shows both promise and limitations as an early-warning system for carbapenemase-producing Enterobacterales in a low …

CF Flach, M Hutinel, M Razavi, C Åhrén, DGJ Larsson - Water research, 2021 - Elsevier
Carbapenemase-producing Enterobacterales (CPE) constitute a significant threat to
healthcare systems. Continuous surveillance is important for the management and early …

[HTML][HTML] High burden and diversity of carbapenemase-producing Enterobacterales observed in wastewater of a tertiary care hospital in Germany

L Carlsen, H Büttner, M Christner, G Franke… - International Journal of …, 2022 - Elsevier
Hospitals are one of the main reservoirs of multi-resistant Enterobacterales (MRE). As MRE
are resistant to the most frequently used antibiotics, therapy for patients with MRE infections …

Carbapenem-resistant bacteria over a wastewater treatment process: Carbapenem-resistant Enterobacteriaceae in untreated wastewater and intrinsically-resistant …

S Araújo, M Sousa, M Tacão, RA Baraúna… - Science of the Total …, 2021 - Elsevier
Although urban wastewater treatment plants (UWWTPs) are important sites for antibiotic
resistance elimination, their limitation in producing resistance-free effluents is recognized …

Genomic analysis reveals high intra-species diversity of Shewanella algae

Z Huang, K Yu, S Fu, Y Xiao, Q Wei… - Microbial …, 2022 - microbiologyresearch.org
Shewanella algae is widely distributed in marine and freshwater habitats, and has been
proved to be an emerging marine zoonotic and human pathogen. However, the genomic …

[HTML][HTML] Extended spectrum beta-lactamase-producing gram-negative bacteria recovered from an Amazonian lake near the city of Belém, Brazil

DY Freitas, S Araujo, ARC Folador… - Frontiers in …, 2019 - frontiersin.org
Aquatic systems have been described as antibiotic resistance reservoirs, where water may
act as a vehicle for the spread of resistant bacteria and resistance genes. We evaluated the …

[HTML][HTML] Prevalence and zoonotic transmission of colistin-resistant and carbapenemase-producing Enterobacterales on German pig farms

N Effelsberg, I Kobusch, S Linnemann, F Hofmann… - One Health, 2021 - Elsevier
The treatment of infections due to colistin-resistant (Col-E) and carbapenemase-producing
(CPE) Enterobacterales challenges clinicians both in human and veterinary medicine …