Cancer has long been considered a genetic disease characterized by a myriad of mutations
that drive cancer progression. Recent accumulating evidence indicates that the …

Introduction Lipidomics focuses on the in-depth analysis of lipids, which are crucial
macromolecules involved in a wide range of metabolic pathways. The increased …

Aggressive and metastatic cancers show enhanced metabolic plasticity, but the precise
underlying mechanisms of this remain unclear. Here we show how two NOP2/Sun RNA …

Tumor-associated macrophages (TAM) are important tumor-promoting cells. However, the
mechanisms underlying how the tumor and its microenvironment reprogram these cells …

Among the most extensively researched processes in the development and treatment of
cancer is inflammatory condition. Although acute inflammation is essential for the wound …

Cancer remains the second leading cause of mortality worldwide. In the course of this
multistage and multifactorial disease, a set of alterations takes place, with genetic and …

Fatty acid uptake and altered metabolism constitute hallmarks of metastasis,, yet evidence of
the underlying biology, as well as whether all dietary fatty acids are prometastatic, is lacking …

Breast cancer is the second common cancer and the leading cause of malignancy among
females overall. Breast cancer stem cells (BCSCs) are a small population of breast cancer …

Although it is established that fatty acid (FA) synthesis supports anabolic growth in cancer,
the role of exogenous FA uptake remains elusive. Here we show that, during acquisition of …

Embraced with apolipoproteins (Apo) B and Apo E, triglyceride-enriched very-low-density
lipoprotein (VLDL) is secreted by the liver into circulation, mainly during post-meal hours …