Mesenchymal stem cell homing to improve therapeutic efficacy in liver disease

M Yuan, X Hu, L Yao, Y Jiang, L Li - Stem Cell Research & Therapy, 2022 - Springer
Mesenchymal stem cell (MSC) transplantation, as an alternative strategy to orthotopic liver
transplantation, has been evaluated for treating end-stage liver disease. Although the …

Mesenchymal stromal cell therapy for liver diseases

M Alfaifi, YW Eom, PN Newsome, SK Baik - Journal of hepatology, 2018 - Elsevier
The therapeutic potential of mesenchymal stromal cells (MSCs) in the treatment of liver
fibrosis is predominantly based on their immunosuppressive properties, and their ability to …

MSCs: biological characteristics, clinical applications and their outstanding concerns

YL Si, YL Zhao, HJ Hao, XB Fu, WD Han - Ageing research reviews, 2011 - Elsevier
Mesenchymal stem cells (MSCs) are multi-potent adult stem cells harboring multi-lineage
differentiation potential and immunosuppressive properties that make MSCs an ideal …

Hepatic stellate cells contribute to progenitor cells and liver regeneration

C Kordes, I Sawitza, S Götze… - The Journal of …, 2014 - Am Soc Clin Investig
Retinoid-storing hepatic stellate cells (HSCs) have recently been described as a liver-
resident mesenchymal stem cell (MSC) population; however, it is not clear whether these …

Mesenchymal stem cell‐based therapy: a new paradigm in regenerative medicine

NK Satija, VK Singh, YK Verma, P Gupta… - Journal of cellular …, 2009 - Wiley Online Library
Introduction• Mesenchymal stem cells and its characteristics• Experimental/preclinical MSC‐
based studies–MSC transplantation–Genetically modified MSC‐based therapy–MSC‐based …

Human mesenchymal stem cells self-renew and differentiate according to a deterministic hierarchy

R Sarugaser, L Hanoun, A Keating, WL Stanford… - PloS one, 2009 - journals.plos.org
Background Mesenchymal progenitor cells (MPCs) have been isolated from a variety of
connective tissues, and are commonly called “mesenchymal stem cells”(MSCs). A stem cell …

Mesenchymal stem cells as therapeutics and vehicles for gene and drug delivery

CD Porada, G Almeida-Porada - Advanced drug delivery reviews, 2010 - Elsevier
Mesenchymal stem cells (MSCs) possess a set of several fairly unique properties which
make them ideally suited both for cellular therapies/regenerative medicine, and as vehicles …

[HTML][HTML] Use of mesenchymal stem cells to treat liver fibrosis: current situation and future prospects

S Berardis, PD Sattwika, M Najimi… - World journal of …, 2015 - ncbi.nlm.nih.gov
Progressive liver fibrosis is a major health issue for which no effective treatment is available,
leading to cirrhosis and orthotopic liver transplantation. However, organ shortage is a reality …

Therapeutic potential of a distinct population of human amniotic fluid mesenchymal stem cells and their secreted molecules in mice with acute hepatic failure

DS Zagoura, MG Roubelakis, V Bitsika, O Trohatou… - Gut, 2012 - gut.bmj.com
Background There is increasing interest in the therapeutic potential of human mesenchymal
stem cells (hMSCs), especially in diseases such as acute hepatic failure (AHF) that are …

Mesenchymal stem cells: a potential therapeutic strategy for neurodegenerative diseases

P Yao, L Zhou, L Zhu, B Zhou, Q Yu - European Neurology, 2020 - karger.com
Neurodegenerative disease is a kind of chronic, progressive nervous system disease
characterized by neuron degeneration or apoptosis. Current treatments cannot prevent the …