[HTML][HTML] Oral delivery of therapeutic peptides and proteins: Technology landscape of lipid-based nanocarriers

S Haddadzadegan, F Dorkoosh… - Advanced drug delivery …, 2022 - Elsevier
The oral administration of therapeutic peptides and proteins is favoured from a patient and
commercial point of view. In order to reach the systemic circulation after oral administration …

[HTML][HTML] Nanostructured lipid carriers (NLCs) as drug delivery platform: Advances in formulation and delivery strategies

M Elmowafy, MM Al-Sanea - Saudi Pharmaceutical Journal, 2021 - Elsevier
NLCs have provoked the incessant impulsion for the development of safe and valuable drug
delivery systems owing to their exceptional physicochemical and then biocompatible …

Surface modification of lipid-based nanoparticles

Y Xu, T Fourniols, Y Labrak, V Préat, A Beloqui… - ACS …, 2022 - ACS Publications
There is a growing interest in the development of lipid-based nanocarriers for multiple
purposes, including the recent increase of these nanocarriers as vaccine components …

A critical review of the use of surfactant-coated nanoparticles in nanomedicine and food nanotechnology

T Miyazawa, M Itaya, GC Burdeos… - International journal …, 2021 - Taylor & Francis
Surfactants, whose existence has been recognized as early as 2800 BC, have had a long
history with the development of human civilization. With the rapid development of …

Nanostructured lipid carriers: Promising drug delivery systems for future clinics

A Beloqui, MÁ Solinís, A Rodríguez-Gascón… - … , biology and medicine, 2016 - Elsevier
During the past decade, the number of studies describing nanostructured lipid carriers
(NLCs)-based formulations has been dramatically increased. The raise in NLC exploitation …

An overview of in vitro, ex vivo and in vivo models for studying the transport of drugs across intestinal barriers

Y Xu, N Shrestha, V Préat, A Beloqui - Advanced Drug Delivery Reviews, 2021 - Elsevier
Oral administration is the most commonly used route for drug delivery owing to its cost-
effectiveness, ease of administration, and high patient compliance. However, the absorption …

Pharmaceutical formulations with P-glycoprotein inhibitory effect as promising approaches for enhancing oral drug absorption and bioavailability

TTL Nguyen, VA Duong, HJ Maeng - Pharmaceutics, 2021 - mdpi.com
P-glycoprotein (P-gp) is crucial in the active transport of various substrates with diverse
structures out of cells, resulting in poor intestinal permeation and limited bioavailability …

BCS class IV drugs: Highly notorious candidates for formulation development

R Ghadi, N Dand - Journal of Controlled Release, 2017 - Elsevier
BCS class IV drugs (eg, amphotericin B, furosemide, acetazolamide, ritonavir, paclitaxel)
exhibit many characteristics that are problematic for effective oral and per oral delivery …

Towards more accurate bioimaging of drug nanocarriers: turning aggregation-caused quenching into a useful tool

J Qi, X Hu, X Dong, Y Lu, H Lu, W Zhao… - Advanced Drug Delivery …, 2019 - Elsevier
One of the current challenges in the monitoring of drug nanocarriers lies in the difficulties in
discriminating the carrier-bound signals from the bulk signals of probes. Environment …

Solid lipid nanoparticles as carriers of natural phenolic compounds

A Borges, V de Freitas, N Mateus, I Fernandes… - Antioxidants, 2020 - mdpi.com
Phenolic compounds are one of the most widespread classes of compounds in nature, with
several beneficial biological effects being associated with their anti-oxidant and anti …