Adult hippocampal neurogenesis has been implicated in cognitive processes, such as
pattern separation, and in the behavioural effects of stress and antidepressants. Young adult …

Serotonin modulates neuroplasticity, especially during early life, and dysfunctions in both
systems likewise contribute to pathophysiology of depression. Recent findings demonstrate …

Major depression is a prevalent illness that increases the risk of several neurological
conditions. These include stroke, cardiovascular disease, and dementia including …

Adult hippocampal neurogenesis is increased by antidepressants, and is required for some
of their behavioral effects. However, it remains unclear whether expanding the population of …

The neurobiology of stress and the neurobiology of social behavior are deeply intertwined.
The social environment interacts with stress on almost every front: social interactions can be …

Highlights•Diverse animal models of depression and anxiety have impaired neurogenesis.•
Neurogenesis is consistently boosted by antidepressants in animal models when animals …

Adolescence represents a critical period for brain and behavioural health and characterised
by the onset of mood, psychotic and anxiety disorders. In rodents, neurogenesis is very …

Selective serotonin reuptake inhibitors (SSRIs) represent the most common treatment for
major depression. However, their efficacy is variable and incomplete. In order to elucidate …

Exposure to stress is one of the best-known negative regulators of adult neurogenesis (AN).
We discuss changes in neurogenesis in relation to exposure to stress, glucocorticoid …

A rapidly growing body of literature indicates that adult neurogenesis in the hippocampus is
sensitive to a variety of environmental factors. The effects of emotionally salient experiences …