Our understanding of the complex molecular processes of living organisms at the molecular
level is growing exponentially. This knowledge, together with a powerful arsenal of tools for …

Crystallography and cryo-electron microscopy have advanced atomic resolution
perspectives of inactive and active states of G protein-coupled receptors (GPCRs), alone …

Research regarding protein–ligand interactions remains a major concern in the fields of
chemistry, biochemistry, pharmacology, and food science. Herein, the interaction of selected …

Compared with green fluorescent protein-based biosensors, red fluorescent protein (RFP)-
based biosensors are inherently advantageous because of reduced phototoxicity …

The incorporation of noncanonical amino acids (ncAAs) into fluorescent proteins is
promising for red-shifting their fluorescence and benefiting tissue imaging with deep …

Due to advances in methods for site-specific incorporation of unnatural amino acids (UAAs)
into proteins, a large number of UAAs with tailored chemical and/or physical properties have …

Proton transfer remains one of the most fundamental processes in chemistry and biology.
Superphotoacids provide an excellent platform to delineate the excited-state proton transfer …

Red fluorescent proteins (RFPs) represent an increasingly popular class of genetically
encodable bioprobes and biomarkers that can advance next‐generation breakthroughs …

Fluorescent proteins (FP) are an integral part of modern biology due to its diverse
biochemical and photophysical properties. The boundaries of FP have been extended …

Herein we report the development of an efficient cellular system for the in vivo biosynthesis
of Tyr-analogs and their concurrent incorporation into target proteins by the residue-specific …