[HTML][HTML] Immunoregulation in cancer-associated cachexia

Q Wu, Z Liu, B Li, Y Liu, P Wang - Journal of Advanced Research, 2024 - Elsevier
Background Cancer-associated cachexia is a multi-organ disorder associated with
progressive weight loss due to a variable combination of anorexia, systemic inflammation …

Hypothalamic neuropeptides and neurocircuitries in Prader Willi syndrome

F Correa‐da‐Silva, E Fliers… - Journal of …, 2021 - Wiley Online Library
Abstract Prader‐Willi Syndrome (PWS) is a rare and incurable congenital
neurodevelopmental disorder, resulting from the absence of expression of a group of genes …

Mitofusin-2 boosts innate immunity through the maintenance of aerobic glycolysis and activation of xenophagy in mice

P Silwal, JK Kim, SM Jeon, JY Lee, YJ Kim… - Communications …, 2021 - nature.com
Mitochondrial function and innate immunity are intimately linked; however, the mechanisms
how mitochondrion-shaping proteins regulate innate host defense remains largely unknown …

Tissue-specific metabolic profile drives iNKT cell function during obesity and liver injury

CF Aguiar, F Corrêa-da-Silva, MB Gonzatti… - Cell reports, 2023 - cell.com
Invariant natural killer T (iNKT) cells are a distinct population of lymphocytes characterized
by their reactivity to glycolipids presented by CD1d. iNKT cells are found throughout the …

M-CSF-and L929-derived macrophages present distinct metabolic profiles with similar inflammatory outcomes

L de Brito Monteiro, GG Davanzo, CF de Aguiar… - Immunobiology, 2020 - Elsevier
Macrophages are essential components of the immune system. Macrophages can be
derived from the bone marrow of mice with either recombinant M-CSF or L929 supernatant …

The levels of ghrelin, glucagon, visfatin and glp-1 are decreased in the peritoneal fluid of women with endometriosis along with the increased expression of the CD10 …

AM Krasnyi, AA Sadekova, TY Smolnova… - International Journal of …, 2022 - mdpi.com
The aim of this study was to evaluate the levels of ten energy metabolism factors: C-peptide,
ghrelin, GIP, GLP-1, glucagon, insulin, leptin, PAI-1 (total), resistin, and visfatin, and to …

Mitofusin 2, a key coordinator between mitochondrial dynamics and innate immunity

IS Kim, P Silwal, EK Jo - Virulence, 2021 - Taylor & Francis
Remodeling of mitochondrial dynamics and mitochondrial morphology plays a pivotal role in
the maintenance of mitochondrial homeostasis in response to pathogenic attacks or stress …

[PDF][PDF] ghrelin 与心血管系统稳态

陆薇薇, 陈瑶, 齐永芬 - 自然杂志, 2021 - jas.shu.edu.cn
摘要ghrelin 是新发现的一种胃肠多肽, 具有强烈的促生长激素释放的作用. ghrelin
及其受体在体内广泛表达, 除具有增加摄食量及调节能量代谢的作用外, 还具有抑制交感神经 …

[PDF][PDF] Ghrelin attenuates the inflammatory response induced by experimental endotoxemia in mice

Z Majid, BM Baqir, DF Al-Shimerty… - INDEXED IN PUBMED …, 2024 - researchgate.net
Aim: The aim of this research is to assess the anti-inflammatory effect of ghrelin in mice
models of polymicrobial sepsis. Materials and Methods: 35 male albino Swiss mice, ages 8 …

Acylated Ghrelin Directly Modulates In Vitro Cytokine Secretion in Lipopolysaccharide-Stimulated Bone Marrow-Derived Macrophages from Male C57BL/6J Mice

AW Wiseman - 2021 - repository.library.carleton.ca
Macrophages are the sentinels of the mammalian body and are involved in both
inflammatory and reparative functions. Upon activation, macrophages reprogram to bias …