EMT‐associated microRNAs and their roles in cancer stemness and drug resistance

G Pan, Y Liu, L Shang, F Zhou… - Cancer …, 2021 - Wiley Online Library
Epithelial‐to‐mesenchymal transition (EMT) is implicated in a wide array of malignant
behaviors of cancers, including proliferation, invasion, and metastasis. Most notably, previou …

[HTML][HTML] LncRNA-miRNA axes in breast cancer: Novel points of interaction for strategic attack

J Venkatesh, MCD Wasson, JM Brown, W Fernando… - Cancer letters, 2021 - Elsevier
Therapeutic effectiveness in breast cancer can be limited by the underlying mechanisms of
pathogenesis, including epithelial-mesenchymal transition (EMT), cancer stem cells (CSCs) …

MSC-induced lncRNA HCP5 drove fatty acid oxidation through miR-3619-5p/AMPK/PGC1α/CEBPB axis to promote stemness and chemo-resistance of gastric cancer

H Wu, B Liu, Z Chen, G Li, Z Zhang - Cell death & disease, 2020 - nature.com
Chemotherapy is the first-tier treatment regime for gastric cancer (GC) patients at advance
stages. Mesenchymal stem cell (MSC) cam affect drug-resistance of GC cells in tumor …

Long noncoding RNAs and exosomal lncRNAs: classification, and mechanisms in breast cancer metastasis and drug resistance

H Yousefi, M Maheronnaghsh, F Molaei, L Mashouri… - Oncogene, 2020 - nature.com
Breast cancer is the most common cancer, and the second cause of cancer-related deaths
(after lung cancer) among women. Developing tumor metastasis and invasion is the most …

Mesenchymal stem/stromal cells in breast cancer development and management

Z Tu, AE Karnoub - Seminars in Cancer Biology, 2022 - Elsevier
Mesenchymal stem/stromal cells (MSCs) encompass a heterogeneous population of
fibroblastic progenitor cells that reside in multiple tissues around the body. They are …

The role of PKM2 nuclear translocation in the constant activation of the NF-κB signaling pathway in cancer-associated fibroblasts

J Gu, X Li, L Zhao, Y Yang, C Xue, Y Gao, J Li… - Cell Death & …, 2021 - nature.com
Cancer-associated fibroblasts (CAFs) play critical roles in cancer progression by regulating
tumor cell proliferation, angiogenesis, and metastasis. Recent studies demonstrated that …

[HTML][HTML] Effect of HPV infection on the occurrence and development of laryngeal cancer: a review

D Yang, Y Shi, Y Tang, H Yin, Y Guo, S Wen… - Journal of …, 2019 - ncbi.nlm.nih.gov
Laryngeal cancer has the second highest incidence of head and neck malignant tumors
worldwide. In recent years, studies have shown that human papillomavirus (HPV) infection …

Cancer stem cells and nucleolin as drivers of carcinogenesis

LS Carvalho, N Gonçalves, NA Fonseca, JN Moreira - Pharmaceuticals, 2021 - mdpi.com
Cancer, one of the most mortal diseases worldwide, is characterized by the gain of specific
features and cellular heterogeneity. Clonal evolution is an established theory to explain …

The network of non-coding RNAs and their molecular targets in breast cancer

F Crudele, N Bianchi, E Reali, M Galasso, C Agnoletto… - Molecular cancer, 2020 - Springer
Abstract Background Non-coding RNAs are now recognized as fundamental components of
the cellular processes. Non-coding RNAs are composed of different classes, including …

Functional interplay between long non-coding RNAs and Breast CSCs

BM Hussen, RK Kheder, ST Abdullah, HJ Hidayat… - Cancer Cell …, 2022 - Springer
Breast cancer (BC) represents aggressive cancer affecting most women's lives globally.
Metastasis and recurrence are the two most common factors in a breast cancer patient's …