Microfluidic organoids-on-a-chip: Quantum leap in cancer research

F Duzagac, G Saorin, L Memeo, V Canzonieri… - Cancers, 2021 - mdpi.com
Simple Summary Organoids, also known as self-organized 3D organ-like clusters, represent
almost a physiological system for studying cells, stem cells, tissues, and diseases, especially …

Microfabricated electrochemical sensing devices

F Sassa, GC Biswas, H Suzuki - Lab on a Chip, 2020 - pubs.rsc.org
Electrochemistry provides possibilities to realize smart microdevices of the next generation
with high functionalities. Electrodes, which constitute major components of electrochemical …

A microfluidic double emulsion platform for spatiotemporal control of pH and particle synthesis

M Rana, R Ahmad, AF Taylor - Lab on a Chip, 2023 - pubs.rsc.org
The temporal control of pH in microreactors such as emulsion droplets plays a vital role in
applications including biomineralisation and microparticle synthesis. Typically, pH changes …

Current progress in long-term and continuous cell metabolite detection using microfluidics

J Shi, L Tong, W Tong, H Chen, M Lan, X Sun… - TrAC Trends in Analytical …, 2019 - Elsevier
Cellular metabolism involves complex sequences of controlled biochemical reactions and
many chemical compounds or metabolites. The quantification of these metabolites will …

Chips for biomaterials and biomaterials for chips: Recent advances at the interface between microfabrication and biomaterials research

APM Guttenplan, Z Tahmasebi Birgani… - Advanced …, 2021 - Wiley Online Library
In recent years, the use of microfabrication techniques has allowed biomaterials studies
which were originally carried out at larger length scales to be miniaturized as so‐called “on …

[HTML][HTML] Advanced in vitro models for renal cell carcinoma therapy design

V Mieville, AW Griffioen, D Benamran… - … et Biophysica Acta (BBA …, 2023 - Elsevier
Renal cell carcinoma (RCC) and its principal subtype, clear cell RCC, are the most
diagnosed kidney cancer. Despite substantial improvement over the last decades, current …

Real‐time pH monitoring of industrially relevant enzymatic reactions in a microfluidic side‐entry reactor (μSER) shows potential for pH control

P Gruber, MPC Marques, P Sulzer… - Biotechnology …, 2017 - Wiley Online Library
Monitoring and control of pH is essential for the control of reaction conditions and reaction
progress for any biocatalytic or biotechnological process. Microfluidic enzymatic reactors are …

Opto-microfluidic system for absorbance measurements in lithium niobate device applied to ph measurements

R Zamboni, A Zaltron, E Izzo, G Bottaro, D Ferraro… - Sensors, 2020 - mdpi.com
The aim of Lab-on-a-chip systems is the downscaling of analytical protocols into microfluidic
devices, including optical measurements. In this context, the growing interest of the scientific …

An electrochemical platform for localized pH control on demand

N Fomina, CA Johnson, A Maruniak, S Bahrampour… - Lab on a Chip, 2016 - pubs.rsc.org
Solution pH is a powerful tool for regulating many kinds of chemical activity, but is generally
treated as a static property defined by a pre-selected buffer. Introducing dynamic control of …

A multimodal digital microfluidic testing platform for antibody-producing cell lines

JT Lant, J Frasheri, T Kwon, CMN Tsang, BB Li… - Lab on a Chip, 2024 - pubs.rsc.org
In recent years, monoclonal antibodies (mAbs) have become a powerful tool in the treatment
of human diseases. Currently, over 100 mAbs have received approval for therapeutic use in …