Antibiotic resistance in wastewater treatment plants: Tackling the black box

CM Manaia, J Rocha, N Scaccia, R Marano… - Environment …, 2018 - Elsevier
Wastewater is among the most important reservoirs of antibiotic resistance in urban
environments. The abundance of carbon sources and other nutrients, a variety of possible …

Freshwater environments as reservoirs of antibiotic resistant bacteria and their role in the dissemination of antibiotic resistance genes

CF Nnadozie, ON Odume - Environmental pollution, 2019 - Elsevier
Freshwater environments are susceptible to possible contamination by residual antibiotics
that are released through different sources, such as agricultural runoffs, sewage discharges …

Target protection as a key antibiotic resistance mechanism

DN Wilson, V Hauryliuk, GC Atkinson… - Nature Reviews …, 2020 - nature.com
Antibiotic resistance is mediated through several distinct mechanisms, most of which are
relatively well understood and the clinical importance of which has long been recognized …

Industrial wastewater treatment plant enriches antibiotic resistance genes and alters the structure of microbial communities

J Bengtsson-Palme, M Milakovic, H Švecová, M Ganjto… - Water research, 2019 - Elsevier
Antibiotic resistance is an emerging global health crisis, driven largely by overuse and
misuse of antibiotics. However, there are examples in which the production of these …

Environmental and health impact of unrecovered API from pharmaceutical manufacturing wastes: A review of contemporary treatment, recycling and management …

ES Okeke, TPC Ezeorba, CO Okoye, Y Chen… - Sustainable Chemistry …, 2022 - Elsevier
Pharmaceutical industries are imminent for the survival of any contemporary society as their
products are valuable for the populace's health and wellness. However, the wastes of these …

ResFinderFG v2. 0: a database of antibiotic resistance genes obtained by functional metagenomics

R Gschwind, S Ugarcina Perovic, M Weiss… - Nucleic Acids …, 2023 - academic.oup.com
Metagenomics can be used to monitor the spread of antibiotic resistance genes (ARGs).
ARGs found in databases such as ResFinder and CARD primarily originate from culturable …

[HTML][HTML] Pollution from azithromycin-manufacturing promotes macrolide-resistance gene propagation and induces spatial and seasonal bacterial community shifts in …

M Milaković, G Vestergaard, JJ González-Plaza… - Environment …, 2019 - Elsevier
Effluents from antibiotic manufacturing may contain high concentrations of antibiotics, which
are the main driving force behind the selection and spread of antibiotic resistance genes in …

[HTML][HTML] Antibiotic-manufacturing sites are hot-spots for the release and spread of antibiotic resistance genes and mobile genetic elements in receiving aquatic …

JJ González-Plaza, K Blau, M Milaković, T Jurina… - Environment …, 2019 - Elsevier
High antibiotic releases from manufacturing facilities have been identified as a risk factor for
antibiotic resistance development in bacterial pathogens. However, the role of antibiotic …

HflXr, a homolog of a ribosome-splitting factor, mediates antibiotic resistance

M Duval, D Dar, F Carvalho… - Proceedings of the …, 2018 - National Acad Sciences
To overcome the action of antibiotics, bacteria have evolved a variety of different strategies,
such as drug modification, target mutation, and efflux pumps. Recently, we performed a …

Degradation of antibiotics and antibiotic resistance genes in fermentation residues by ionizing radiation: a new insight into a sustainable management of antibiotic …

Y Shen, L Chu, R Zhuan, X Xiang, H Sun… - Journal of environmental …, 2019 - Elsevier
Antibiotic fermentative residues are categorized into hazardous wastes in China due to the
existence of antibiotic resistance genes (ARGs) and residual antibiotics How to treat and …