Gestational diabetes mellitus (GDM) has become a major public health problem and one of
the most discussed issues in modern obstetrics. GDM is associated with serious adverse …

Supplementation with prebiotic polyphenol rutin is a potential dietary therapy for type 2
diabetes prevention in adults with obesity, based on previous glycaemic improvement in …

Highlights•Islet amyloid polypeptide (IAPP) fibrillation causes β-cell cytotoxicity•Structure
plays an important role in anti-fibrillation activity of nutraceuticals•Some anti-fibrillation food …

The pathogenesis of type 2 diabetes (T2D) is highly related to the abnormal self-assembly of
the human islet amyloid polypeptide (hIAPP) into amyloid aggregates. To inhibit hIAPP …

Islet amyloid polypeptide (IAPP) fibrillation induces β-cell dysfunction and toxicity in patients
with type 2 diabetes. Cytotoxicity is caused by the ability of IAPP fibrils and fibrillar …

Numerous neurodegenerative disorders are characterized by protein misfolding and
aggregation. The mechanism of protein aggregation is intricate, and it is very challenging to …

Soluble epoxide hydrolase (sEH) contributes to the pathophysiology of neurodegenerative
diseases by decreasing the epoxyeicosatrienoic acids/dihydroeicosatrienoic acids ratio and …

This Special Issue of the International Journal of Molecular Sciences is focused on bioactive
peptides in foods or hydrolyzates of food by-products, the methods for the extraction and …

Protein aggregation is associated with various diseases caused by protein misfolding.
Among them, amylin deposition is a prominent feature of type 2 diabetes. At present, the …

Abstract Type 2 diabetes (T2D) is linked to the apoptosis of insulin-producing β-cells due to
the aberrant fibrillation of the human islet amyloid polypeptide (hIAPP or amylin) to cytotoxic …