The glycine receptor chloride channel (GlyR) is a member of the nicotinic acetylcholine
receptor family of ligand-gated ion channels. Functional receptors of this family comprise five …

Proton channels exist in a wide variety of membrane proteins where they transport protons
rapidly and efficiently. Usually the proton pathway is formed mainly by water molecules …

Introduction: Preclinical and clinical studies suggest that cannabidiol (CBD) found in
Cannabis spp. has broad therapeutic value. CBD products can currently be purchased …

Cartilage lesions in degenerative osteoarthritis (OA) are involved with pathological
microenvironmental alterations induced by inflammatory macrophages, and apoptotic and/or …

L-Glycine: a novel antiinflammatory, immunomodulatory, and c... : Current Opinion in Clinical
Nutrition & Metabolic Care L-Glycine: a novel antiinflammatory, immunomodulatory, and …

Hepatocellular carcinoma (HCC) is the most common primary malignant tumor of the liver
and the third most common cause of cancer-related death worldwide. HCC is caused by …

Glycine is a non-essential amino acid with many functions and effects. Glycine can bind to
specific receptors and transporters that are expressed in many types of cells throughout an …

The polymerase chain reaction was used to screen human peripheral blood mononuclear
cells (PBMC) and Jurkat cells for the presence of GABAA receptor subunit mRNAs. Positive …

Volatile anesthetics (VAs) have been in clinical use for a very long time. Their mechanism of
action is yet to be fully delineated, but multiple ion channels have been reported as targets …

In recent years, it has become appreciated that immune cells have different metabolic
profiles depending on their activation status. During sepsis, circulating leukocytes go …