NOS2 and COX-2 Co-Expression Promotes Cancer Progression: A Potential Target for Developing Agents to Prevent or Treat Highly Aggressive Breast Cancer

LL Coutinho, EL Femino, AL Gonzalez… - International Journal of …, 2024 - mdpi.com
Nitric oxide (NO) and reactive nitrogen species (RNS) exert profound biological impacts
dictated by their chemistry. Understanding their spatial distribution is essential for …

Anti-Inflammatory Drug Repurposing for Intranasal Delivery: Ketoprofen Nanoemulgel Development for the Treatment of Glioma

PC Pires, M Correia, F Veiga… - Engineering Proceedings, 2023 - mdpi.com
The anti-inflammatory drug ketoprofen has shown promising results in the field of drug
repurposing for the treatment of brain cancer, but currently developed formulations are for …

Overexpressed CFLAR drives 5-fluorouracil sensitivity and immune response in breast cancer by regulating reactive oxygen species

C Wang, J He, X Tong, L Zhang, L Song - 2023 - researchsquare.com
Breast cancer (BRCA), the most frequent malignancy in women, is a highly heterogeneous
disease. Chemoresistant is the main factor for the BRCA treatment failure. However, the …