Prognostic significances of overexpression MYC and/or BCL2 in R-CHOP-treated diffuse large B-cell lymphoma: A Systematic review and meta-analysis

L Li, Y Li, X Que, X Gao, Q Gao, M Yu, K Ma, Y Xi… - Scientific Reports, 2018 - nature.com
Numerous studies have investigated the prognostic values of MYC and/or BCL2 protein
overexpression in diffuse large B-cell lymphoma (DLBCL). However, the results still …

A clinician's guide to double hit lymphomas

CY Cheah, Y Oki, JR Westin… - British Journal of …, 2015 - Wiley Online Library
Double hit lymphomas (DHL) represent a subset of highly aggressive B‐cell malignancies
characterized by the presence of recurrent cytogenetic rearrangements affecting MYC and …

Expression profiles of MYC protein and MYC gene rearrangement in lymphomas

KM Chisholm, CD Bangs, CE Bacchi… - The American journal …, 2015 - journals.lww.com
MYC translocations are a defining feature of Burkitt lymphoma and a group of diffuse large B-
cell lymphoma (DLBCL) with inferior outcome. However, the clinical relevance of MYC gene …

The miR-17∼ 92 microRNA cluster is a global regulator of tumor metabolism

S Izreig, B Samborska, RM Johnson, A Sergushichev… - Cell reports, 2016 - cell.com
A central hallmark of cancer cells is the reprogramming of cellular metabolism to meet the
bioenergetic and biosynthetic demands of malignant growth. Here, we report that the miR …

MYC translocation and/or BCL 2 protein expression are associated with poor prognosis in diffuse large B‐cell lymphoma

K Kawamoto, H Miyoshi, N Yoshida… - Cancer …, 2016 - Wiley Online Library
Genomic alterations and protein expression levels have been established as prognostic
factors for survival in patients with diffuse large B‐cell lymphoma (DLBCL). In particular …

Rituximab in combination with cyclophosphamide, doxorubicin, vincristine, and prednisone (R-CHOP) in diffuse large B-cell lymphoma

M Candelaria… - Therapeutic Advances in …, 2021 - journals.sagepub.com
Background: Diffuse large B-cell lymphoma (DLBCL) is the most frequent non-Hodgkin
lymphoma worldwide. The current standard of care is chemoimmunotherapy with an R …

An analysis of MYC and EBV in diffuse large B-cell lymphomas associated with angioimmunoblastic T-cell lymphoma and peripheral T-cell lymphoma not otherwise …

JC Hoffmann, KM Chisholm, A Cherry, J Chen… - Human Pathology, 2016 - Elsevier
Composite diffuse large B-cell lymphomas (DLBCLs) with peripheral T-cell lymphomas
(PTCLs) are rare co-occurrences with poorly understood pathologic features. Herein, we …

Advances in pathobiology of primary central nervous system lymphoma

XL Yang, YB Liu - Chinese medical journal, 2017 - mednexus.org
Objective: Primary central nervous system lymphoma (PCNSL) is a specific type of non-
Hodgkin lymphoma with poor prognosis. The rare incidence of this disease and difficulty to …

Prognostic Significance of BCL-2 and BCL-6 Expression in MYC-positive DLBCL

L Li, X Zhang, T Zhang, Z Song, G Hu, W Li, L Li… - … Myeloma and Leukemia, 2018 - Elsevier
Background Double-expression lymphoma (DEL) is a rare subgroup of diffuse large B-cell
lymphoma (DLBCL), which has coexpression of MYC and BCL-2. Coexpression of MYC and …

c‐MYC and p53 expression highlight starry‐sky pattern as a favourable prognostic feature in R‐CHOP‐treated diffuse large B‐cell lymphoma

A Bouroumeau, L Bussot, T Bonnefoix… - The Journal of …, 2021 - Wiley Online Library
Diffuse large B‐cell lymphoma (DLBCL) is a clinically heterogeneous entity, in which the first‐
line treatment currently consists of an immuno‐chemotherapy regimen (R‐CHOP). However …