Nanocarriers address intracellular barriers for efficient drug delivery, overcoming drug resistance, subcellular targeting and controlled release
J Liu, H Cabral, P Mi - Advanced Drug Delivery Reviews, 2024 - Elsevier
The cellular barriers are major bottlenecks for bioactive compounds entering into cells to
accomplish their biological functions, which limits their biomedical applications …
accomplish their biological functions, which limits their biomedical applications …
[HTML][HTML] Cell penetrating peptide: A potent delivery system in vaccine development
B Hasannejad-Asl, F Pooresmaeil… - Frontiers in …, 2022 - frontiersin.org
One of the main obstacles to most medication administrations (such as the vaccine
constructs) is the cellular membrane's inadequate permeability, which reduces their …
constructs) is the cellular membrane's inadequate permeability, which reduces their …
[图书][B] CPP, cell-penetrating peptides
Ü Langel - 2019 - Springer
The genesis of cell-penetrating peptide research (CPP; also known as prote/peptide
transduction domains, PTD, or Trojan peptides) was born from the publication of two parallel …
transduction domains, PTD, or Trojan peptides) was born from the publication of two parallel …
Cell-penetrating peptides for transmucosal delivery of proteins
Enabling non-invasive delivery of proteins across the mucosal barriers promises improved
patient compliance and therapeutic efficacies. Cell-penetrating peptides (CPPs) are …
patient compliance and therapeutic efficacies. Cell-penetrating peptides (CPPs) are …
[HTML][HTML] Advances in aptamers-based applications in breast cancer: drug delivery, therapeutics, and diagnostics
T Gholikhani, S Kumar, H Valizadeh… - International Journal of …, 2022 - mdpi.com
Aptamers are synthetic single-stranded oligonucleotides (such as RNA and DNA) evolved in
vitro using Systematic Evolution of Ligands through Exponential enrichment (SELEX) …
vitro using Systematic Evolution of Ligands through Exponential enrichment (SELEX) …
Therapeutic nucleic acids in regenerative medicine and tissue repair
In the vanguard of biomedical innovation, regenerative medicine emerges as a
transformative paradigm, concentrating its efforts on rectifying tissue deficits and functional …
transformative paradigm, concentrating its efforts on rectifying tissue deficits and functional …
[HTML][HTML] Toxicity Studies of Cardiac-Targeting Peptide Reveal a Robust Safety Profile
DA Sahagun, JB Lopuszynski, KS Feldman… - Pharmaceutics, 2024 - mdpi.com
Targeted delivery of therapeutics specifically to cardiomyocytes would open up new frontiers
for common conditions like heart failure. Our prior work using a phage display methodology …
for common conditions like heart failure. Our prior work using a phage display methodology …
[PDF][PDF] Application and Immunogenicity of Aptamers in Cancer Therapy
A Ghazizadeh, R Amazadeh, M Ziyamolki, A Olfati… - Biomed Res, 2023 - biomedrb.com
Aptamers are short single-stranded nucleic acid (DNA or RNA) or peptide sequences with a
unique three-dimensional structure that bind to their targets with high specificity and affinity …
unique three-dimensional structure that bind to their targets with high specificity and affinity …
Therapeutic potential of CPPs
Ü Langel - CPP, Cell-Penetrating Peptides, 2023 - Springer
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