Nanocarrier drug delivery systems: characterization, limitations, future perspectives and implementation of artificial intelligence

SZ Alshawwa, AA Kassem, RM Farid, SK Mostafa… - Pharmaceutics, 2022 - mdpi.com
There has been an increasing demand for the development of nanocarriers targeting
multiple diseases with a broad range of properties. Due to their tiny size, giant surface area …

Polymeric nanoparticles for delivery of natural bioactive agents: recent advances and challenges

M Elmowafy, K Shalaby, MH Elkomy, OA Alsaidan… - Polymers, 2023 - mdpi.com
In the last few decades, several natural bioactive agents have been widely utilized in the
treatment and prevention of many diseases owing to their unique and versatile therapeutic …

Current status of alginate in drug delivery

DM Hariyadi, N Islam - Advances in pharmacological and …, 2020 - Wiley Online Library
Alginate is one of the natural polymers that are often used in drug‐and protein‐delivery
systems. The use of alginate can provide several advantages including ease of preparation …

Polymer nano-systems for the encapsulation and delivery of active biomacromolecular therapeutic agents

M Machtakova, H Thérien-Aubin… - Chemical society …, 2022 - pubs.rsc.org
Biomacromolecular therapeutic agents, particularly proteins, antigens, enzymes, and nucleic
acids are emerging as powerful candidates for the treatment of various diseases and the …

An up‐to‐date review on alginate nanoparticles and nanofibers for biomedical and pharmaceutical applications

A Dodero, S Alberti, G Gaggero… - Advanced Materials …, 2021 - Wiley Online Library
Alginate is a naturally occurring polysaccharide commonly derived from brown algae cell
walls which possesses unique features that make it extremely promising for several …

Recent advances in cellulose, pectin, carrageenan and alginate-based oral drug delivery systems

N Raghav, C Vashisth, N Mor, P Arya… - International Journal of …, 2023 - Elsevier
Polymers-based drug delivery systems constitute one of the highly explored thrust areas in
the field of the medicinal and pharmaceutical industries. In the past years, the properties of …

Structures, properties, and bioengineering applications of alginates and hyaluronic acid

S Zhang, J Dong, R Pan, Z Xu, M Li, R Zang - Polymers, 2023 - mdpi.com
In recent years, polymeric materials have been used in a wide range of applications in a
variety of fields. In particular, in the field of bioengineering, the use of natural biomaterials …

Nanostructured lipid carriers for oral bioavailability enhancement of exemestane: formulation design, in vitro, ex vivo, and in vivo studies

A Singh, YR Neupane, B Mangla, K Kohli - Journal of pharmaceutical …, 2019 - Elsevier
Exemestane (EXE) is a novel oral steroidal aromatase inhibitor approved for the treatment of
breast cancer. However, its oral clinical application is limited because of low aqueous …

Hazard assessment of polymeric nanobiomaterials for drug delivery: what can we learn from literature so far

S Jesus, M Schmutz, C Som, G Borchard… - … in bioengineering and …, 2019 - frontiersin.org
The physicochemical properties of nanobiomaterials, such as their small size and high
surface area ratio, make them attractive, novel drug-carriers, with increased cellular …

Chitosan-coated bovine serum albumin nanoparticles for topical tetrandrine delivery in glaucoma: in vitro and in vivo assessment

SES Radwan, RM El-Moslemany, RA Mehanna… - Drug Delivery, 2022 - Taylor & Francis
Glaucoma is one of the leading causes of blindness. Therapies available suffer from several
drawbacks including low bioavailability, repeated administration and poor patient …