Current cancer management strategies fail to adequately treat malignancies with
multivariable dose-restricting factors such as systemic toxicity and multi-drug resistance …

Currently approximately 10 million people die each year due to cancer, and cancer is the
cause of every sixth death worldwide. Tremendous efforts and progress have been made …

Mycotoxins are highly diverse secondary metabolites produced in nature by a wide variety of
fungus which causes food contamination, resulting in mycotoxicosis in animals and humans …

Pseudomonas exotoxin A (PE) is a highly toxic protein secreted by the opportunistic
pathogen Pseudomonas aeruginosa. The modular structure and corresponding mechanism …

Synthetic cells, artificial cell‐like particles, capable of autonomously synthesizing RNA and
proteins based on a DNA template, are emerging platforms for studying cellular functions …

Cancer remains one of the leading causes of death worldwide. Conventional therapeutic
strategies usually offer limited specificity, resulting in severe side effects and toxicity to …

Immunotoxins and antibody-drug conjugates are protein-based drugs combining a target-
specific binding domain with a cytotoxic domain. Such compounds are potentially …

Immunotoxins are antibody-toxin bifunctional molecules that rely on intracellular toxin action
to kill target cells. Target specificity is determined via the binding attributes of the chosen …

While the survival rate has increased due to treatments for breast cancer, the quality of life
has decreased because of the side effects of chemotherapy. Various toxins are being …

Immunotoxins (ITs) are attractive anticancer modalities aimed at cancer-specific delivery of
highly potent cytotoxic protein toxins. An IT consists of a targeting domain (an antibody …