Astrocytes in the regulation of cerebrovascular functions
M Cohen‐Salmon, L Slaoui, N Mazaré, A Gilbert… - Glia, 2021 - Wiley Online Library
Astrocytes are the most numerous type of neuroglia in the brain and have a predominant
influence on the cerebrovascular system; they control perivascular homeostasis, the integrity …
influence on the cerebrovascular system; they control perivascular homeostasis, the integrity …
Astrocytes: dissecting their diverse roles in amyotrophic lateral sclerosis and frontotemporal dementia
CF Valori, C Sulmona, L Brambilla, D Rossi - Cells, 2023 - mdpi.com
Amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD) are fatal
neurodegenerative disorders often co-occurring in the same patient, a feature that suggests …
neurodegenerative disorders often co-occurring in the same patient, a feature that suggests …
Varying perivascular astroglial endfoot dimensions along the vascular tree maintain perivascular‐interstitial flux through the cortical mantle
The glymphatic system is a recently defined brain‐wide network of perivascular spaces
along which cerebrospinal fluid (CSF) and interstitial solutes exchange. Astrocyte endfeet …
along which cerebrospinal fluid (CSF) and interstitial solutes exchange. Astrocyte endfeet …
Gap junctions and hemichannels composed of connexins and pannexins mediate the secondary brain injury following intracerebral hemorrhage
Simple Summary Intracerebral hemorrhage (ICH) is a leading medical problem without
effective treatment options. The poor prognosis is attributed to the primary brain injury of the …
effective treatment options. The poor prognosis is attributed to the primary brain injury of the …
Mlc1-Expressing Perivascular Astrocytes Promote Blood–Brain Barrier Integrity
In the mammalian brain, perivascular astrocytes (PAs) closely juxtapose blood vessels and
are postulated to have important roles in the control of vascular physiology, including …
are postulated to have important roles in the control of vascular physiology, including …
Connexin 43: an interface connecting neuroinflammation to depression
H Jiang, Y Zhang, ZZ Wang, NH Chen - Molecules, 2023 - mdpi.com
Major depressive disorder (MDD) is a leading chronic mental illness worldwide,
characterized by anhedonia, pessimism and even suicidal thoughts. Connexin 43 (Cx43) …
characterized by anhedonia, pessimism and even suicidal thoughts. Connexin 43 (Cx43) …
Astrocytes in rare neurological conditions: Morphological and functional considerations
K Ravi, MJ Paidas, A Saad… - Journal of Comparative …, 2021 - Wiley Online Library
Astrocytes are a population of central nervous system (CNS) cells with distinctive
morphological and functional characteristics that differ within specific areas of the brain and …
morphological and functional characteristics that differ within specific areas of the brain and …
The CaMKII/MLC1 Axis Confers Ca2+-Dependence to Volume-Regulated Anion Channels (VRAC) in Astrocytes
MS Brignone, A Lanciotti, A Michelucci, C Mallozzi… - Cells, 2022 - mdpi.com
Astrocytes, the main glial cells of the central nervous system, play a key role in brain volume
control due to their intimate contacts with cerebral blood vessels and the expression of a …
control due to their intimate contacts with cerebral blood vessels and the expression of a …
[HTML][HTML] Megalencephalic leukoencephalopathy with subcortical cysts protein-1: A new calcium-sensitive protein functionally activated by endoplasmic reticulum …
MS Brignone, A Lanciotti, P Molinari, C Mallozzi… - Neurobiology of …, 2024 - Elsevier
Background MLC1 is a membrane protein highly expressed in brain perivascular astrocytes
and whose mutations account for the rare leukodystrophy (LD) megalencephalic …
and whose mutations account for the rare leukodystrophy (LD) megalencephalic …
Identification of the GlialCAM interactome: the G protein-coupled receptors GPRC5B and GPR37L1 modulate megalencephalic leukoencephalopathy proteins
M Alonso-Gardón, X Elorza-Vidal… - Human Molecular …, 2021 - academic.oup.com
Abstract Megalencephalic Leukoencephalopathy with subcortical Cysts (MLC) is a type of
vacuolating leukodystrophy, which is mainly caused by mutations in MLC1 or GLIALCAM …
vacuolating leukodystrophy, which is mainly caused by mutations in MLC1 or GLIALCAM …