Osteoarthritis (OA) is a common joint disease with a high disability rate. In addition, OA not
only causes great physiological and psychological harm to patients, but also puts great …

Osteoarthritis is the most prevalent chronic and debilitating joint disease, resulting in huge
medical and socioeconomic burdens. Intra-articular administration of agents is clinically …

Silk fibroin (SF) and sericin (SS), the two major proteins of silk, are attractive biomaterials
with great potential in tissue engineering and regenerative medicine. However, their …

Osteochondral repair remains a major challenge in current clinical practice despite
significant advances in tissue engineering. In particular, the lateral integration of …

Osteochondral defects (OCD) cannot be efficiently repaired due to the unique physical
architecture and the pathological microenvironment including enhanced oxidative stress …

Myocardial infarction (MI) is one of cardiovascular diseases that pose a serious threat to
human health. The pathophysiology of MI is complex and contains several sequential …

Osteochondral (OC) repair is an extremely challenging topic due to the complex biphasic
structure and poor intrinsic regenerative capability of natural osteochondral tissue. In …

The incidence of osteochondral defect is increasing year by year, but there is still no widely
accepted method for repairing the defect. Hydrogels loaded with bioactive molecules have …

Osteochondral defects are characterized by injuries to both cartilage and subchondral bone,
which is a result of trauma, inflammation, or inappropriate loading. Due to the unique …

Osteochondral defect (OCD) regeneration remains challenging because of the hierarchy of
the native tissue including both the articular cartilage and the subchondral bone …