Alternative splicing and the evolution of phenotypic novelty

SJ Bush, L Chen… - … Transactions of the …, 2017 - royalsocietypublishing.org
Alternative splicing, a mechanism of post-transcriptional RNA processing whereby a single
gene can encode multiple distinct transcripts, has been proposed to underlie morphological …

Impact of gene gains, losses and duplication modes on the origin and diversification of vertebrates

C Cañestro, R Albalat, M Irimia… - Seminars in cell & …, 2013 - Elsevier
The study of the evolutionary origin of vertebrates has been linked to the study of genome
duplications since Susumo Ohno suggested that the successful diversification of vertebrate …

An update of DIVERGE software for functional divergence analysis of protein family

X Gu, Y Zou, Z Su, W Huang, Z Zhou… - Molecular biology …, 2013 - academic.oup.com
DIVERGE is a software system for phylogeny-based analyses of protein family evolution and
functional divergence. It provides a suite of statistical tools for selection and prioritization of …

Genome-wide identification of evolutionarily conserved alternative splicing events in flowering plants

S Chamala, G Feng, C Chavarro… - … in bioengineering and …, 2015 - frontiersin.org
Alternative splicing (AS) plays important roles in many plant functions, but its conservation
across the plant kingdom is not known. We describe a methodology to identify AS events …

A serpin gene from a parasitoid wasp disrupts host immunity and exhibits adaptive alternative splicing

Z Yan, Q Fang, J Song, L Yang, S Xiao, J Wang… - PLoS …, 2023 - journals.plos.org
Alternative splicing (AS) is a major source of protein diversity in eukaryotes, but less is
known about its evolution compared to gene duplication (GD). How AS and GD interact is …

Gene length and expression level shape genomic novelties

V Grishkevich, I Yanai - Genome research, 2014 - genome.cshlp.org
Gene duplication and alternative splicing are important mechanisms in the production of
genomic novelties. Previous work has shown that a gene's family size and the number of …

Living organisms author their read-write genomes in evolution

JA Shapiro - Biology, 2017 - mdpi.com
Evolutionary variations generating phenotypic adaptations and novel taxa resulted from
complex cellular activities altering genome content and expression:(i) Symbiogenetic cell …

The evolutionary relationship between alternative splicing and gene duplication

LP Iñiguez, G Hernández - Frontiers in genetics, 2017 - frontiersin.org
The protein diversity that exists today has resulted from various evolutionary processes. It is
well known that gene duplication (GD) along with the accumulation of mutations are …

Changes in alternative splicing in response to domestication and polyploidization in wheat

K Yu, M Feng, G Yang, L Sun, Z Qin, J Cao… - Plant …, 2020 - academic.oup.com
Alternative splicing (AS) occurs extensively in eukaryotes as an important mechanism for
regulating transcriptome complexity and proteome diversity, but variation in the AS …

Evolutionarily conserved alternative splicing across monocots

W Mei, L Boatwright, G Feng, JC Schnable… - Genetics, 2017 - academic.oup.com
One difficulty when identifying alternative splicing (AS) events in plants is distinguishing
functional AS from splicing noise. One way to add confidence to the validity of a splice …