This paper attempts to summarize current knowledge about immune responses to vaccines
that correlate with protection. Although the immune system is redundant, almost all current …

Tuberculosis (TB) is an infectious disease caused by Mycobacterium tuberculosis. As a
result of the coronavirus disease 2019 (COVID-19) pandemic, the global TB mortality rate in …

This report compiles and summarizes all recommendations from CDC's Advisory Committee
on Immunization Practices (ACIP) for use of meningococcal vaccines in the United States …

Many vaccines induce protective immunity via antibodies. Systems biology approaches
have been used to determine signatures that can be used to predict vaccine-induced …

Meningococcal disease describes the spectrum of infections caused by Neisseria
meningiditis, including meningitdis, bacteremia, and bacteremic pneumonia. Two …

Identification of immune correlates of protection after vaccination is an important part of
vaccinology for both theoretical and practical reasons. The terminology and definition of …

Reverse Vaccinology (RV) is a widely used approach to identify potential vaccine
candidates (PVCs) by screening the proteome of a pathogen through computational …

The utility of wild-type outer membrane vesicle (wtOMV) vaccines against serogroup B
(MenB) meningococcal disease has been explored since the 1970s. Public health …

Background An effective, affordable, multivalent meningococcal conjugate vaccine is
needed to prevent epidemic meningitis in the African meningitis belt. Data on the safety and …

Eculizumab has opened new horizons in the treatment of complement-mediated disorders.
Prophylactic and immunization strategies against the risk of Nesseria spp. infections are …