The N‐end rule pathway and regulation by proteolysis
A Varshavsky - Protein science, 2011 - Wiley Online Library
The N‐end rule relates the regulation of the in vivo half‐life of a protein to the identity of its N‐
terminal residue. Degradation signals (degrons) that are targeted by the N‐end rule pathway …
terminal residue. Degradation signals (degrons) that are targeted by the N‐end rule pathway …
Toxin–Antitoxin systems: their role in persistence, biofilm formation, and pathogenicity
Y Wen, E Behiels, B Devreese - Pathogens and disease, 2014 - academic.oup.com
One of the most pertinent recent outcomes of molecular microbiology efforts to understand
bacterial behavior is the discovery of a wide range of toxin–antitoxin (TA) systems that are …
bacterial behavior is the discovery of a wide range of toxin–antitoxin (TA) systems that are …
Suppression of hepatitis C virus by the flavonoid quercetin is mediated by inhibition of NS3 protease activity
L Bachmetov, M Gal‐Tanamy, A Shapira… - Journal of viral …, 2012 - Wiley Online Library
Phytochemicals exert antiviral activity and may play a potential therapeutic role in hepatitis C
virus (HCV) infection. In this work, we aimed to isolate NS3 inhibitors from traditional Indian …
virus (HCV) infection. In this work, we aimed to isolate NS3 inhibitors from traditional Indian …
[HTML][HTML] Plant ribosome-inactivating proteins: Progesses, challenges and biotechnological applications (and a few digressions)
MS Fabbrini, M Katayama, I Nakase, R Vago - Toxins, 2017 - mdpi.com
Plant ribosome-inactivating protein (RIP) toxins are EC3. 2.2. 22 N-glycosidases, found
among most plant species encoded as small gene families, distributed in several tissues …
among most plant species encoded as small gene families, distributed in several tissues …
Protein engineering: a new frontier for biological therapeutics
PH Tobin, DH Richards, RA Callender… - Current drug …, 2014 - ingentaconnect.com
Protein engineering holds the potential to transform the metabolic drug landscape through
the development of smart, stimulusresponsive drug systems. Protein therapeutics are a …
the development of smart, stimulusresponsive drug systems. Protein therapeutics are a …
[HTML][HTML] Removal of hepatitis C virus-infected cells by a zymogenized bacterial toxin
A Shapira, S Shapira, M Gal-Tanamy, R Zemel… - PloS one, 2012 - journals.plos.org
Hepatitis C virus (HCV) infection is a major cause of chronic liver disease and has become a
global health threat. No HCV vaccine is currently available and treatment with antiviral …
global health threat. No HCV vaccine is currently available and treatment with antiviral …
Shiga toxin a subunit effector polypeptides, shiga toxin effector scaffolds, and cell-targeting molecules for site-specific conjugation
P Eric, E Willert - 2020 - Google Patents
YOHYSYJDKVYCJI-UHFFFAOYSA-N n-[3-[[6-[3-(trifluoromethyl) anilino] pyrimidin-4-yl]
amino] phenyl] cyclopropanecarboxamide Chemical compound FC (F)(F) C1= CC= CC …
amino] phenyl] cyclopropanecarboxamide Chemical compound FC (F)(F) C1= CC= CC …
[图书][B] Investigating the interactors of the Blumeria effector BEC1054
H Pennington - 2016 - core.ac.uk
Wheat (Triticum spp.) and barley (Hordeum vulgare) are economically important crops
belonging to the Poaceae, which are mainly grown in the Northern Hemisphere (Hejgaard et …
belonging to the Poaceae, which are mainly grown in the Northern Hemisphere (Hejgaard et …
Recombinant self-assembling nanoparticles for cancer therapy based on toxin and venom compounds
R Díaz Ocaña - 2020 - ddd.uab.cat
La plataforma desenvolupada d'enginyeria de proteïnes auto-acoblables permet dissenyar
nanopartícules únicament proteiques (NPs) capaces d'atacar i actuar selectivament sobre …
nanopartícules únicament proteiques (NPs) capaces d'atacar i actuar selectivament sobre …
Shiga toxin a subunit effector polypeptides, shiga toxin effector scaffolds, and cell-targeting molecules for site-specific conjugation
P Eric, E WILLERT - 2018 - Google Patents
YOHYSYJDKVYCJI-UHFFFAOYSA-N n-[3-[[6-[3-(trifluoromethyl) anilino] pyrimidin-4-yl]
amino] phenyl] cyclopropanecarboxamide Chemical compound FC (F)(F) C1= CC= CC …
amino] phenyl] cyclopropanecarboxamide Chemical compound FC (F)(F) C1= CC= CC …