Bone defects combined with tumors, infections, or other bone diseases are challenging in
clinical practice. Autologous and allogeneic grafts are two main traditional remedies, but …

Bioelectrical phenomenon in natural bone has been well recognized for its role in bone
development and fracture healing. For example, the piezoelectricity induced modulation in …

Bone regeneration is a highly synchronized process that requires multiple biochemical,
bioelectrical, mechanical, and other physiological cues. The restoration and delivery of …

Piezoelectric materials, with their unique ability for mechanical‐electrical energy conversion,
have been widely applied in important fields such as sensing, energy harvesting …

Piezoelectric materials can directly transduce electrical and mechanical energy, making
them attractive for applications such as sensors, actuators and energy harvesting devices …

With the aging of population and the rapid improvement of public health and medical level in
recent years, people have had an increasing demand for orthopedic implants. However …

Abstract Four-dimensional (4D) bioprinting, in which the concept of time is integrated with
three-dimensional (3D) bioprinting as the fourth dimension, has currently emerged as the …

The process of bone repair and regeneration requires multiple physiological cues including
biochemical, electrical and mechanical-that act together to ensure functional recovery …

Hard tissue repair and regeneration cost hundreds of billions of dollars annually worldwide,
and the need has substantially increased as the population has aged. Hard tissues include …

Surface charge on biomaterials is emerging as a crucial determinant of regulating cells
responses impacting cells signaling in tissue treatment. The dynamic cell-material …