Stress is recognized as an important issue in basic and clinical neuroscience research,
based upon the founding historical studies by Walter Canon and Hans Selye in the past …

Glucocorticoids (GCs) are steroid hormones widely used for the treatment of inflammation,
autoimmune diseases, and cancer. To exert their broad physiological and therapeutic …

It is well established that stress has a major impact on memory, driven by the concerted
action of various stress mediators on the brain. Recent years, however, have seen …

The past decade has seen several critical advances in our understanding of hypothalamic–
pituitary–adrenal (HPA) axis regulation. Homeostatic physiological circuits need to integrate …

The hypothalamo-pituitary-adrenocortical (HPA axis) is required for stress adaptation.
Activation of the HPA axis causes secretion of glucocorticoids, which act on multiple organ …

The hypothalamic–pituitary–adrenal (HPA) axis is the major neuroendocrine axis regulating
homeostasis in mammals. Glucocorticoid hormones are rapidly synthesized and secreted …

The hypothalamic–pituitary–adrenal (HPA) axis, a neuroendocrine network that controls
hormonal responses to internal and external challenges in an organism's environment …

Adrenal glucocorticoids are major modulators of multiple functions, including energy
metabolism, stress responses, immunity, and cognition. The endogenous secretion of …

Glucocorticoid hormones (cortisol and corticosterone-CORT) are the effector hormones of
the hypothalamic-pituitary-adrenal (HPA) axis neuroendocrine system. CORT is a systemic …

Stress affects a constellation of physiological systems in the body and evokes a rapid shift in
many neurobehavioral processes. A growing body of work indicates that the …