Trisomy 21, the presence of a supernumerary chromosome 21, results in a collection of
clinical features commonly known as Down syndrome (DS). DS is among the most …

Approximately 3% to 5% of pregnancies are complicated by birth defects or genetic
disorders. 1 Chromosomal abnormalities are present in approximately 1 in 150 live births, 2 …

Imprinted genes control fetal and placental growth in mice and in rare human syndromes,
but the role of these genes in sporadic intrauterine growth restriction (IUGR) is less well …

Gastroschisis offers the intriguing epidemiological situation of a pandemic, strongly
associated with very low maternal age. Identifying gastroschisis, and distinguishing it from …

Congenital cystic lesions of the lung in fetuses are rare. The most common malformations of
the lower respiratory tract are congenital cystic adenomatoid malformation and …

Sirenomelia is a very rare limb anomaly in which the normally paired lower limbs are
replaced by a single midline limb. This study describes the prevalence, associated …

The latest Zika virus (ZIKV) outbreak has reached epidemic proportions as it spreads
throughout South and Central America. In November 2015, the Brazilian Ministry of Health …

Biliary cysts (BC) are rare dilatations of different parts of a biliary tract. They account for
approximately 1% of all benign biliary diseases. BC occur the most frequently in Asian and …

Stillbirth is one of the most common adverse pregnancy outcomes in the United States,
occurring in one out of every 200 pregnancies. There is a paucity of information on the …

Background/Purpose: Accurate prenatal diagnosis of complex anatomic connections and
associated anomalies has only been possible recently with the use of ultrasonography …