Plant flavonoids on oxidative stress-mediated kidney inflammation

S Alsawaf, F Alnuaimi, S Afzal, RM Thomas… - Biology, 2022 - mdpi.com
Simple Summary Increased stress is often observed in patients with kidney diseases,
contributing to renal injury progression. Flavonoids are naturally occurring plant compounds …

The Protective Effects of Nutraceutical Components in Methotrexate-Induced Toxicity Models—An Overview

GE Marin, MA Neag, CC Burlacu, AD Buzoianu - Microorganisms, 2022 - mdpi.com
There are multiple concerns associated with methotrexate (MTX), widely recognized for anti-
neoplastic and anti-inflammatory effects in life-threatening disease conditions, ie, acute …

Separation and purification of target flavonoids using covalently connected MOFs@ boronic acid-functionalized-COFs magnetic hybrids: Precise identification and …

S Liu, Z Hu, X Yan, S Geng, X Zhao, H Ou… - Separation and …, 2023 - Elsevier
The magnetic boronate based sorbents have been widely used to separation of cis-diol
containing flavonoids. However, It's still challenging due to its chemical structural fragility …

Dual inhibition of glycolysis and glutaminolysis for synergistic therapy of rheumatoid arthritis

S Ahmed, CB Mahony, A Torres, J Murillo-Saich… - Arthritis Research & …, 2023 - Springer
Background Synovial fibroblasts in rheumatoid arthritis (RAFLS) exhibit a pathological
aberration of glycolysis and glutaminolysis. Henceforth, we aimed to investigate if dual …

[HTML][HTML] Naringin attenuates oxidative stress, inflammation, apoptosis, and oxidative DNA damage in acrylamide-induced nephrotoxicity in rats

V Gelen, S Yıldırım, E Şengül, A Çınar… - Asian Pacific Journal …, 2022 - journals.lww.com
Objective: To explore the possible effects of naringin on acrylamide-induced nephrotoxicity
in rats. Methods: Sprague-Dawley rats weighing 200-250 g were randomly divided into five …

The Preventive Effects of Naringin and Naringenin against Paclitaxel‐Induced Nephrotoxicity and Cardiotoxicity in Male Wistar Rats

SS Khaled, HA Soliman… - Evidence‐Based …, 2022 - Wiley Online Library
This study assessed the preventive properties of naringin and naringenin on paclitaxel‐
induced nephrotoxicity and cardiotoxicity in adult male Wistar rats. Intraperitoneal injection …

L‐carnitine reverses methotrexate‐induced nephrotoxicity in experimental rat model: Insight on SIRT1/PGC‐1α/Nrf2/HO‐1 axis

SM Radwan, M Alqulaly, MY Elsaeed… - Journal of Applied …, 2023 - Wiley Online Library
Methotrexate (MTX) is a chemotherapeutic agent used for treating several types of cancer as
well as psoriasis and rheumatoid arthritis, but its use is limited due to its nephrotoxicity. The …

Naringin attenuates the diabetic neuropathy in STZ-induced type 2 diabetic Wistar rats

MF Ahmad, N Naseem, I Rahman, N Imam, H Younus… - Life, 2022 - mdpi.com
The application of traditional medicines for the treatment of diseases, including diabetic
neuropathy (DN), has received great attention. The aim of this study was to investigate the …

L-methionine protects against nephrotoxicity induced by methotrexate through modulation of redox status and inflammation

WM Abdel-Wahab, NS Daifalla, AE Essawy - Redox Report, 2023 - Taylor & Francis
Objective: Methotrexate (MTX) is a drug used in the treatment of cancer and autoimmune
disorders; however, its clinical use is limited because of serious side effects including renal …

Protective effects of naringin on colistin‐induced damage in rat testicular tissue: Modulating the levels of Nrf‐2/HO‐1, AKT‐2/FOXO1A, Bax/Bcl2/Caspase‐3, and …

NA Kankılıç, H Şimşek, N Akaras, C Gür… - … of Biochemical and …, 2024 - Wiley Online Library
Antimicrobial agent resistance has become a growing health issue across the world. Colistin
(COL) is one of the drugs used in the treatment of multidrug‐resistant bacteria resulting in …