Interleukin-1β signaling in osteoarthritis–chondrocytes in focus

Z Jenei-Lanzl, A Meurer, F Zaucke - Cellular Signalling, 2019 - Elsevier
Osteoarthritis (OA) can be regarded as a chronic, painful and degenerative disease that
affects all tissues of a joint and one of the major endpoints being loss of articular cartilage. In …

Immunoporosis: immunology of osteoporosis—role of T cells

RK Srivastava, HY Dar, PK Mishra - Frontiers in immunology, 2018 - frontiersin.org
The role of immune system in various bone pathologies, such as osteoporosis, osteoarthritis,
and rheumatoid arthritis is now well established. This had led to the emergence of a modern …

A proteome-scale map of the SARS-CoV-2–human contactome

DK Kim, B Weller, CW Lin, D Sheykhkarimli… - Nature …, 2023 - nature.com
Understanding the mechanisms of coronavirus disease 2019 (COVID-19) disease severity
to efficiently design therapies for emerging virus variants remains an urgent challenge of the …

Osteoimmunology: a current update of the interplay between bone and the immune system

C Guder, S Gravius, C Burger, DC Wirtz… - Frontiers in …, 2020 - frontiersin.org
Immunology, already a discipline in its own right, has become a major part of many different
medical fields. However, its relationship to orthopedics and trauma surgery has …

Oxidative stress as a key modulator of cell fate decision in osteoarthritis and osteoporosis: a narrative review

J Riegger, A Schoppa, L Ruths… - Cellular & molecular …, 2023 - Springer
During aging and after traumatic injuries, cartilage and bone cells are exposed to various
pathophysiologic mediators, including reactive oxygen species (ROS), damage-associated …

Lactobacillus rhamnosus attenuates bone loss and maintains bone health by skewing Treg-Th17 cell balance in Ovx mice

L Sapra, HY Dar, A Bhardwaj, A Pandey, S Kumari… - Scientific reports, 2021 - nature.com
Osteoporosis is a systemic-skeletal disorder characterized by enhanced fragility of bones
leading to increased rates of fractures and morbidity in large number of populations …

[HTML][HTML] Lactobacillus acidophilus inhibits bone loss and increases bone heterogeneity in osteoporotic mice via modulating Treg-Th17 cell balance

HY Dar, P Shukla, PK Mishra, R Anupam, RK Mondal… - Bone reports, 2018 - Elsevier
Osteoporosis is one of the most important but often neglected bone disease associated with
aging and postmenopausal condition leading to bone loss and fragility. Probiotics have …

[HTML][HTML] Zinc based biodegradable metals for bone repair and regeneration: Bioactivity and molecular mechanisms

P Li, J Dai, Y Li, D Alexander, J Čapek… - Materials Today Bio, 2024 - Elsevier
Bone fractures and critical-size bone defects are significant public health issues, and clinical
treatment outcomes are closely related to the intrinsic properties of the utilized implant …

Bifidobacterium longum Ameliorates Ovariectomy-Induced Bone Loss via Enhancing Anti-Osteoclastogenic and Immunomodulatory Potential of Regulatory B Cells …

L Sapra, N Shokeen, K Porwal, C Saini… - Frontiers in …, 2022 - frontiersin.org
Discoveries in the last few years have emphasized the existence of an enormous breadth of
communication between osteo-immune systems. These discoveries fuel novel approaches …

The rising era of “Immunoporosis”: Role of immune system in the pathophysiology of osteoporosis

RK Srivastava, L Sapra - Journal of Inflammation Research, 2022 - Taylor & Francis
Discoveries in the last few years have emphasized the existence of an enormous breadth of
communication between bone and the immune system in maintaining skeletal homeostasis …