Translational investigation of the therapeutic potential of cannabidiol (CBD): toward a new age

JA Crippa, FS Guimarães, AC Campos… - Frontiers in …, 2018 - frontiersin.org
Background: Among the many cannabinoids in the cannabis plant, cannabidiol (CBD) is a
compound that does not produce the typical subjective effects of marijuana. Objectives: The …

Cannabidiol (CBD) use in psychiatric disorders: A systematic review

S Bonaccorso, A Ricciardi, C Zangani, S Chiappini… - Neurotoxicology, 2019 - Elsevier
Abstract Cannabidiol (CBD) and Δ9-tetrahydrocannabinol (THC) are the most represented
phytocannabinoids in Cannabis sativa plants. However, CBD may present with a different …

Antidepressant effects of a single dose of ayahuasca in patients with recurrent depression: a SPECT study

RF Sanches, F de Lima Osório… - Journal of clinical …, 2016 - journals.lww.com
Ayahuasca is an Amazonian botanical hallucinogenic brew which contains
dimethyltryptamine, a 5-HT 2A receptor agonist, and harmine, a monoamine-oxidase A …

Use of cannabidiol (CBD) for the treatment of chronic pain

I Urits, K Gress, K Charipova, K Habib, D Lee… - Best Practice & …, 2020 - Elsevier
Chronic pain can be recurrent or constant pain that lasts for longer than 3 months and can
result in disability, suffering, and a physical disturbance. Related to the complex nature of …

Safety and side effects of cannabidiol, a Cannabis sativa constituent

M Machado Bergamaschi… - Current drug …, 2011 - ingentaconnect.com
Cannabidiol (CBD), a major nonpsychotropic constituent of Cannabis, has multiple
pharmacological actions, including anxiolytic, antipsychotic, antiemetic and anti …

Multiple mechanisms involved in the large-spectrum therapeutic potential of cannabidiol in psychiatric disorders

AC Campos, FA Moreira, FV Gomes… - … of the Royal …, 2012 - royalsocietypublishing.org
Cannabidiol (CBD) is a major phytocannabinoid present in the Cannabis sativa plant. It
lacks the psychotomimetic and other psychotropic effects that the main plant compound Δ 9 …

The effects of cannabidiol, a non-intoxicating compound of cannabis, on the cardiovascular system in health and disease

A Kicman, M Toczek - International journal of molecular sciences, 2020 - mdpi.com
Cannabidiol (CBD) is a non-intoxicating and generally well-tolerated constituent of cannabis
which exhibits potential beneficial properties in a wide range of diseases, including …

A systematic review of the antipsychotic properties of cannabidiol in humans

TA Iseger, MG Bossong - Schizophrenia research, 2015 - Elsevier
Despite extensive study over the past decades, available treatments for schizophrenia are
only modestly effective and cause serious metabolic and neurological side effects …

A randomised controlled trial of vaporised Δ9-tetrahydrocannabinol and cannabidiol alone and in combination in frequent and infrequent cannabis users: acute …

N Solowij, S Broyd, L Greenwood, H van Hell… - European archives of …, 2019 - Springer
Access to cannabis and cannabinoid products is increasing worldwide for recreational and
medicinal use. Two primary compounds within cannabis plant matter, Δ 9 …

Phytocannabinoids as novel therapeutic agents in CNS disorders

AJ Hill, CM Williams, BJ Whalley… - Pharmacology & …, 2012 - Elsevier
The Cannabis sativa herb contains over 100 phytocannabinoid (pCB) compounds and has
been used for thousands of years for both recreational and medicinal purposes. In the past …