Older adult participation in cancer clinical trials: a systematic review of barriers and interventions

MS Sedrak, RA Freedman, HJ Cohen… - CA: a cancer journal …, 2021 - Wiley Online Library
Cancer is a disease of aging and, as the world's population ages, the number of older
persons with cancer is increasing and will make up a growing share of the oncology …

Updated recommendations regarding the management of older patients with breast cancer: a joint paper from the European Society of Breast Cancer Specialists …

L Biganzoli, NML Battisti, H Wildiers… - The Lancet …, 2021 - thelancet.com
Breast cancer is increasingly prevalent in older adults and is a substantial part of routine
oncology practice. However, management of breast cancer in this population is challenging …

Geriatric assessment–driven intervention (GAIN) on chemotherapy-related toxic effects in older adults with cancer: a randomized clinical trial

D Li, CL Sun, H Kim, E Soto-Perez-de-Celis… - JAMA …, 2021 - jamanetwork.com
Importance Although geriatric assessment–driven intervention improves patient-centered
outcomes, its influence on chemotherapy-related toxic effects remains unknown. Objective …

Practical assessment and management of vulnerabilities in older patients receiving chemotherapy: ASCO guideline for geriatric oncology

SG Mohile, W Dale, MR Somerfield… - Journal of clinical …, 2018 - ascopubs.org
Purpose To provide guidance regarding the practical assessment and management of
vulnerabilities in older patients undergoing chemotherapy. Methods An Expert Panel was …

Cancer statistics for adults aged 85 years and older, 2019

CE DeSantis, KD Miller, W Dale… - CA: a cancer journal …, 2019 - Wiley Online Library
Adults aged 85 years and older, the “oldest old,” are the fastest‐growing age group in the
United States, yet relatively little is known about their cancer burden. Combining data from …

Anticipating the “Silver Tsunami”: prevalence trajectories and co-morbidity burden among older cancer survivors in the United States

SM Bluethmann, AB Mariotto, JH Rowland - … Epidemiology, Biomarkers & …, 2016 - AACR
Background: Cancer survivors are a growing population, due in large part to the aging of the
baby boomer generation and the related “silver tsunami” facing the US health care system …

Functional versus chronological age: geriatric assessments to guide decision making in older patients with cancer

E Soto-Perez-de-Celis, D Li, Y Yuan, YM Lau… - The Lancet …, 2018 - thelancet.com
As the worldwide population ages, oncologists are often required to make difficult and
complex decisions regarding the treatment of older people (aged 65 years and older) with …

Modernizing clinical trial eligibility criteria: recommendations of the American Society of Clinical Oncology–Friends of Cancer Research brain metastases working …

NU Lin, T Prowell, AR Tan, M Kozak… - Journal of Clinical …, 2017 - ascopubs.org
Purpose Broadening trial eligibility to improve accrual and access and to better reflect
intended-to-treat populations has been recognized as a priority. Historically, patients with …

How is geriatric assessment used in clinical practice for older adults with cancer? A survey of cancer providers by the American Society of Clinical Oncology

W Dale, GR Williams, A R. MacKenzie… - JCO oncology …, 2021 - ascopubs.org
PURPOSE: For patients with cancer who are older than 65 years, the 2018 ASCO Guideline
recommends geriatric assessment (GA) be performed. However, there are limited data on …

Communication with older patients with cancer using geriatric assessment: a cluster-randomized clinical trial from the National Cancer Institute Community Oncology …

SG Mohile, RM Epstein, A Hurria, CE Heckler… - JAMA …, 2020 - jamanetwork.com
Importance Older patients with cancer and their caregivers worry about the effects of cancer
treatment on aging-related domains (eg, function and cognition). Quality conversations with …