Low voltage-activated (LVA) T-type calcium channels play critical roles in the excitability of
many cell types and are a focus of research aimed both at understanding the physiological …

Low voltage-activated (LVA) T-type calcium channels are well regarded as a key
mechanism underlying the generation of neuronal burst-firing. Their low threshold for …

The olfactory bulb (OB) is central to the sense of smell, as it is the site of the first synaptic
relay involved in the processing of odor information. Odor sensations are first transduced by …

Sensory processing shapes our perception. In mammals, odor information is encoded by
combinatorial activity patterns of olfactory bulb (OB) glomeruli. Glomeruli are richly …

Loss of excitatory amino acid transporters (EAATs) has been implicated in a number of
human diseases including spinocerebellar ataxias, Alzhiemer's disease and motor neuron …

Key points• Neurons in the brain express a diversity of ion channels to impart specialized
functional properties.• At least three distinct voltage gated calcium channel gene families are …

Metabotropic glutamate receptors (mGluRs) are G-protein-coupled receptors that modulate
excitatory neurotransmission and synaptic plasticity. The group I mGluRs (mGluR1 and …

T‐type channels are unique among the voltage‐gated calcium channels in their fast kinetics
and low voltages of activation and inactivation, the latter two features allowing them to …

Key points Regular‐spiking interneurons in the hippocampal stratum oriens exhibit a form of
long‐term potentiation of excitatory transmission that is independent of NMDA receptors but …

Neurons in the cerebellar nuclei fire at accelerated rates for prolonged periods after trains of
synaptic inhibition that interrupt spontaneous firing. Both in vitro and in vivo, however, this …