[HTML][HTML] Effect of gum Arabic on oxidative stress and inflammation in adenine–induced chronic renal failure in rats

BH Ali, I Al-Husseni, S Beegam, A Al-Shukaili… - PloS one, 2013 - journals.plos.org
Inflammation and oxidative stress are known to be involved in the pathogenesis of chronic
kidney disease in humans, and in chronic renal failure (CRF) in rats. The aim of this work …

[HTML][HTML] Targeting ROS/NF-κB signaling pathway by the seedless black Vitis vinifera polyphenols in CCl4-intoxicated kidney, lung, brain, and spleen in rats

NH Habashy, AS Kodous, MM Abu-Serie - Scientific reports, 2021 - nature.com
Carbon tetrachloride (CCl4) is an abundant environmental pollutant that can generate free
radicals and induce oxidative stress in different human and animal organs like the kidney …

[HTML][HTML] Neurological sequel of chronic kidney disease: From diminished Acetylcholinesterase activity to mitochondrial dysfunctions, oxidative stress and inflammation …

MK Mazumder, R Paul, P Bhattacharya, A Borah - Scientific reports, 2019 - nature.com
With increasing prevalence, chronic kidney disease (CKD) has become a global health
problem. Due to the retention of uremic toxins, electrolytes and water, and the resultant …

[HTML][HTML] p-Cresol sulfate caused behavior disorders and neurodegeneration in mice with unilateral nephrectomy involving oxidative stress and neuroinflammation

CY Sun, JR Li, YY Wang, SY Lin, YC Ou, CJ Lin… - International journal of …, 2020 - mdpi.com
Protein-bound uremic toxins, such as p-cresol sulfate (PCS), can be accumulated with
declined renal function and aging and is closely linked with central nervous system (CNS) …

The effect of curcumin on oxaliplatin and cisplatin neurotoxicity in rats: some behavioral, biochemical, and histopathological studies

MS Al Moundhri, S Al-Salam, A Al Mahrouqee… - Journal of Medical …, 2013 - Springer
Cisplatin is commonly used against several solid tumors, and oxaliplatin is an effective
cytotoxic drug used in colorectal cancer. A major clinical issue affecting 10–40% of patients …

Functional and histological effects of Anthurium schlechtendalii Kunth extracts on adenine-induced kidney damage of adult Wistar rats

AL Calderón-Garcidueñas, DM Barradas-Dermitz… - Toxicon, 2023 - Elsevier
Anthurium schlechtendalii Kunth is used by the Zoque group in southeastern Mexico for
kidney and urinary diseases, but its safety and effectiveness are unproven, therefore a …

[HTML][HTML] Indoxyl sulfate caused behavioral abnormality and neurodegeneration in mice with unilateral nephrectomy

CY Sun, JR Li, YY Wang, SY Lin, YC Ou, CJ Lin… - Aging (Albany …, 2021 - ncbi.nlm.nih.gov
Abstract Chronic Kidney Disease (CKD) and neurodegenerative diseases are aging-related
diseases. CKD with declined renal function is associated with an elevation of circulating …

[HTML][HTML] Acacia senegal gum attenuates systemic toxicity in CCl4-intoxicated rats via regulation of the ROS/NF-κB signaling pathway

MM Abu-Serie, AF Hamouda, NH Habashy - Scientific reports, 2021 - nature.com
Acacia senegal (AS) gum (Gum Arabic) is a natural emulsifier exudate from the branches
and trunk of Acacia trees and it is recognized by the Food and Drug Administration (FDA) …

[HTML][HTML] Uremia induces upregulation of cerebral tissue oxidative/inflammatory cascade, down-regulation of Nrf2 pathway and disruption of blood brain barrier

W Jing, B Jabbari, ND Vaziri - American journal of translational …, 2018 - ncbi.nlm.nih.gov
Chronic kidney disease (CKD) results in various central nervous systems (CNS) disorders
including cognitive dysfunction, depression, anxiety, movement disorders, seizures and …

New model for adenine-induced chronic renal failure in mice, and the effect of gum acacia treatment thereon: comparison with rats

BH Ali, S Al-Salam, M Al Za'abi, MI Waly… - … of pharmacological and …, 2013 - Elsevier
Introduction This study aimed at comparing the effects of feeding mice and rats with adenine
to induce a state of chronic renal failure (CRF), and to assess the effect of treatment with …