To facilitate the process of aging healthily and prevent age-related health problems, efforts
to properly understand aging mechanisms and develop effective and affordable anti-aging …

BACKGROUND Modern reproductive behavior in most developed countries is characterized
by delayed parenthood. Older gametes are generally less fertile, accumulating and …

Objective To examine the potential effects of lifestyle factors on male reproductive health.
Evidence of a global decline in human sperm quality over recent decades has been …

The average age of fathers at first pregnancy has risen significantly over the last decade
owing to various variables, including a longer life expectancy, more access to contraception …

Activation of caspase, externalization of phosphatidyl serine, change in the mitochondrial
membrane potential, and DNA fragmentation are apoptosis markers found in human …

Methods This retrospective descriptive study included 2681 male patients who underwent
semen analysis at Clínica Las Condes (CLC), Santiago, Chile, between January 2014 and …

Male fertility has been seen to be declining, prompting for more effective and accessible
means of its assessment. Artificial intelligence methods have been effective toward …

Circular RNA (circRNA) is a closed, single-stranded transcript widely detected in eukaryotes.
Recent studies indicate that the levels of circRNAs change with age in various tissues in …

Introduction Advanced paternal age of reproduction is an increasing trend, especially in
developed countries and areas. This trend results in elevated risks of adverse reproductive …

Parenthood at an older age is becoming a trend among men, especially in the most
developed societies. Aging has a significant impact on male fertility. Older men exhibit …