Estrogen biosynthesis and signal transduction in ovarian disease
XL Xu, ZY Huang, K Yu, J Li, XW Fu… - Frontiers in …, 2022 - frontiersin.org
Estrogen mainly binds to estrogen receptors (ERs) to regulate menstrual cycles and
reproduction. The expression of ERalpha (ERα), ERbeta (ERβ), and G-protein-coupled …
reproduction. The expression of ERalpha (ERα), ERbeta (ERβ), and G-protein-coupled …
Basic aspects of endometrial receptivity in PCOS patients
ADS Pathare, I Hinduja, RC Mahadik - Molecular Biology Reports, 2022 - Springer
Abstract Polycystic Ovarian Syndrome (PCOS) is an endocrine disorder commonly affecting
the reproductive capacity of women leading to infertility. PCOS-related infertility is majorly …
the reproductive capacity of women leading to infertility. PCOS-related infertility is majorly …
Discovery of novel bicyclic phenylselenyl-containing hybrids: an orally bioavailable, potential, and multiacting class of estrogen receptor modulators against endocrine …
X Deng, B Xie, Q Li, Y Xiao, Z Hu, X Deng… - Journal of Medicinal …, 2022 - ACS Publications
Breast cancer (BC) is a multifactorial disease and is prone to drug resistance during
treatment. In this study, we described a new class of multifunctional estrogen receptor (ER) …
treatment. In this study, we described a new class of multifunctional estrogen receptor (ER) …
LncRNA GAS5 inhibits miR-579-3p to activate SIRT1/PGC-1α/Nrf2 signaling pathway to reduce cell pyroptosis in sepsis-associated renal injury
H Ling, Q Li, ZP Duan, YJ Wang… - American Journal of …, 2021 - journals.physiology.org
Sepsis is a life-threatening condition that can lead to several organ failures including kidney.
In this study, we investigated the roles of GAS5 and miR-579-3p in regulating cell pyroptosis …
In this study, we investigated the roles of GAS5 and miR-579-3p in regulating cell pyroptosis …
Alterations of endometrial epithelial–mesenchymal transition and MAPK signalling components in women with PCOS are partially modulated by metformin in vitro
M Hu, Y Zhang, X Li, P Cui, J Li… - Molecular Human …, 2020 - academic.oup.com
Growing evidence suggests that epithelial–mesenchymal transition (EMT) and its regulator
mitogen-activated protein kinase (MAPK) contribute to endometria-related reproductive …
mitogen-activated protein kinase (MAPK) contribute to endometria-related reproductive …
AURKA enhances the glycolysis and development of ovarian endometriosis through ERβ
Y Sun, S Zhang, X Zhang, G Li, F Sun, M Wang… - …, 2024 - academic.oup.com
Ovarian endometriosis (EMs) is a benign, estrogen-dependent gynecological disorder.
Estrogen receptor beta (ERβ), a nuclear receptor for estradiol, plays an important role in the …
Estrogen receptor beta (ERβ), a nuclear receptor for estradiol, plays an important role in the …
Uncovering novel therapeutic targets in glucose, nucleotides and lipids metabolism during cancer and neurological diseases
SM Jovičić - International Journal of Immunopathology and …, 2024 - journals.sagepub.com
Background Cell metabolism functions without a stop in normal and pathological cells.
Different metabolic changes occur in the disease. Cell metabolism influences biochemical …
Different metabolic changes occur in the disease. Cell metabolism influences biochemical …
Enrichment analyses of diseases and pathways associated with precocious puberty using PrecocityDB
Precocious puberty (PP) is an important endocrine disorder affecting children globally.
Several genes, SNPs and comorbidities are reported to be associated with PP; however, this …
Several genes, SNPs and comorbidities are reported to be associated with PP; however, this …