The carbon− carbon triple bond of alkynes is one of the basic functional groups, its reactions
belonging to the foundations of organic chemistry. In the past decades, acetylene chemistry …

Parallel library synthesis is an important tool for drug discovery because it enables the
synthesis of closely related analogues in parallel via robust and general synthetic …

Abstract Mixed NHC–Pd–PPh 3 complexes with a methoxyethyl-substituted N-heterocyclic
carbene (NHC) were synthesised and characterised by NMR, HRMS, elemental analysis …

A general approach for the synthesis of 2-alkynyl-d-glucal derivatives has been achieved
through a ligand and copper-free Sonogashira coupling of 2-iodo-3, 4, 6-tri-O-acetyl-d …

A novel, inexpensive, and efficient palladium-, copper-, ligand-, and amine-free Sonogashira-
type cross-coupling reaction of terminal alkynes with unreactive aryl fluorides in the …

Abnormal N-heterocyclic carbenes of the N-fused heterocycles were employed in stabilizing
a series of PEPPSI (Pyridine Enhanced Precatalyst Preparation Stabilization and Initiation) …

3D-Printing has been used to build hollow NMR tube/spinner combinations out of NMR-
transparent polyamide. The whole 3D-print has been processed inside a glove box and …

Employing Burkhard Konig's l-(+)-tartaric acid-dimethyl urea (DMU) mixture as an efficient
catalyst or as solvent for the Michael addition of various chalcones with N …

In spite of their various pharmacological properties the anti-inflammatory potential of benzo
[c] phenanthridines remained underexplored. Thus, for the first time PDE4 inhibitory …

The catalytic activity of dimeric [Pd {C 6 H 2 (–CH= NOH)–(OMe) 2-2, 3}(µ–Cl)] 2 complex as
an efficient, air, and moisture-tolerant catalyst was investigated in Suzuki cross-coupling …