Natural products derived from medicinal plants and microbes might act as a game-changer in breast cancer: A comprehensive review of preclinical and clinical studies

RK Singla, X Wang, R Gundamaraju… - Critical Reviews in …, 2023 - Taylor & Francis
Breast cancer (BC) is the most prevalent neoplasm among women. Genetic and
environmental factors lead to BC development and on this basis, several preventive …

[HTML][HTML] The International Natural Product Sciences Taskforce (INPST) and the power of Twitter networking exemplified through# INPST hashtag analysis

RK Singla, R De, T Efferth, B Mezzetti, MS Uddin… - Phytomedicine, 2023 - Elsevier
Background The development of digital technologies and the evolution of open innovation
approaches have enabled the creation of diverse virtual organizations and enterprises …

Natural kinase inhibitors for the treatment and management of endometrial/uterine cancer: preclinical to clinical studies

RK Singla, S Behzad, J Khan, C Tsagkaris… - Frontiers in …, 2022 - frontiersin.org
Endometrial cancer (EC) is the sixth most prevalent type of cancer among women. Kinases,
enzymes mediating the transfer of adenosine triphosphate (ATP) in several signaling …

Marine Streptomyces sp. PGC 39: A treasure trove of new antimicrobial agents, macrolidycin, and pyrachlomycin

R Ahmad, MI Tousif, M Nazir, A Yaqoob, SAA Shah… - Food Bioscience, 2024 - Elsevier
Abstract Macrolidycin (1) and pyrachlomycin (2) were isolated from the culture broth of the
marine bacterium Streptomyces sp. GSCWU 39. The isolates were characterized due to 1D …

[PDF][PDF] Screening and evaluation of potential microbial bio-activators used in sewage sludge composting

M Bostubayeva, E Baimbetova… - Caspian Journal of …, 2023 - cjes.guilan.ac.ir
Forty pure microbial cultures have been isolated from sewage sludge to develop
biopreparations using the microbiological screening method. Among all studied …

Occurrence and dissemination of antibiotics and antibiotic resistance in aquatic environment and its ecological implications: a review

A Singh, SG Pratap, A Raj - Environmental Science and Pollution …, 2024 - Springer
The occurrence of antibiotics and antibiotic-resistant bacteria (ARBs), genes (ARGs), and
mobile genetic elements (MGEs) in aquatic systems is growing global public health concern …

In Silico and In Vitro Screening Constituents of Eclipta alba Leaf Extract to Reveal Antimicrobial Potential

RK Sharma, S Bibi, H Chopra, MS Khan… - Evidence‐Based …, 2022 - Wiley Online Library
Phytochemicals have been shown to possess multiple bioactives and have been reported to
showcase many medicinal effects. A similar kind of evaluation of phytoconstituents for their …

Translational informatics for natural products as antidepressant agents

RK Singla, S Joon, L Shen, B Shen - Frontiers in Cell and …, 2022 - frontiersin.org
Depression, a neurological disorder, is a universally common and debilitating illness where
social and economic issues could also become one of its etiologic factors. From a global …

Synergistic Antifungal Interaction between Pseudomonas aeruginosa LV Strain Metabolites and Biogenic Silver Nanoparticles against Candida auris

LFA Spoladori, GM Andriani, IM Castro, HT Suzukawa… - Antibiotics, 2023 - mdpi.com
Candida auris has been found to be a persistent colonizer of human skin and a successful
pathogen capable of causing potentially fatal infection, especially in immunocompromised …

Exploration of natural product leads for multitarget-based treatment of cancer—computational to experimental journey

RK Singla, MT Scotti, S Kar - Frontiers in Pharmacology, 2022 - frontiersin.org
Natural products are being used for the treatment of various diseases and disorders. A
series of studies are undergoing from computational to clinical level to assess the …