Arginase: an old enzyme with new tricks

RB Caldwell, HA Toque, SP Narayanan… - Trends in …, 2015 - cell.com
Arginase has roots in early life-forms. It converts L-arginine to urea and ornithine. The former
provides protection against NH 3; the latter serves to stimulate cell growth and other …

Arginase as a potential biomarker of disease progression: a molecular imaging perspective

G S. Clemente, A van Waarde, I F. Antunes… - International Journal of …, 2020 - mdpi.com
Arginase is a widely known enzyme of the urea cycle that catalyzes the hydrolysis of L-
arginine to L-ornithine and urea. The action of arginase goes beyond the boundaries of …

A synthetic erectile optogenetic stimulator enabling blue‐light‐inducible penile erection

T Kim, M Folcher, MDE Baba… - Angewandte Chemie …, 2015 - Wiley Online Library
Precise spatiotemporal control of physiological processes by optogenetic devices inspired
by synthetic biology may provide novel treatment opportunities for gene‐and cell‐based …

Basic science evidence for the link between erectile dysfunction and cardiometabolic dysfunction

B Musicki, AJ Bella, TJ Bivalacqua… - The Journal of …, 2015 - academic.oup.com
Introduction Although clinical evidence supports an association between cardiovascular/
metabolic diseases (CVMD) and erectile dysfunction (ED), scientific evidence for this link is …

The role of arginase in aging: a systematic review

J Moretto, C Girard, C Demougeot - Experimental Gerontology, 2019 - Elsevier
Aging is a normal, progressive and multi-step degeneration in the physiological functions
and metabolic processes of living organisms until death. It represents the main risk factor for …

Arginase as a critical prooxidant mediator in the binomial endothelial dysfunction‐atherosclerosis

LA Rabelo, FO Ferreira, V Nunes-Souza… - Oxidative Medicine …, 2015 - Wiley Online Library
Arginase is a metalloenzyme which hydrolyzes L‐arginine to L‐ornithine and urea. Since its
discovery, in the early 1900s, this enzyme has gained increasing attention, as literature …

Low-intensity electrostimulation enhances neuroregeneration and improves erectile function in a rat model of cavernous nerve injury

M Sturny, S Karakus, R Fraga-Silva… - The journal of sexual …, 2022 - academic.oup.com
Background Neurogenic erectile dysfunction (ED) following radical prostatectomy (RP) is a
frequent complication often leading to erectile tissue remodeling and permanent ED. Low …

Apelin-13 protects corpus cavernosum against fibrosis induced by high-fat diet in an MMP-dependent mechanism

M Sturny, L Anguenot, FP Costa-Fraga… - The Journal of …, 2021 - academic.oup.com
Background An increased fibrosis of the corpora cavernosa is a prevalent process that
underlies most cases of erectile dysfunction. Apelin, an endogenous circulating peptide, has …

Diminazene protects corpus cavernosum against hypercholesterolemia‐induced injury

RA Fraga‐Silva, FP Costa‐Fraga… - The journal of sexual …, 2015 - academic.oup.com
Introduction Angiotensin‐converting enzyme 2 (ACE2) is a key enzyme of the renin
angiotensin system, which breaks down angiotensin II and forms angiotensin‐(1–7). In …

Horseradish (Moringa oleifera) seed and leaf inclusive diets modulates activities of enzymes linked with hypertension, and lipid metabolites in high-fat fed rats

SI Oyeleye, TA Olasehinde, AO Ademosun… - PharmaNutrition, 2019 - Elsevier
This study examined the effects of Horseradish leaves and seeds inclusive diets on
angiotensin-I converting enzyme (ACE) and arginase activities and lipid [total cholesterol …