[HTML][HTML] Sodium-glucose cotransporter-2 inhibitors: Understanding the mechanisms for therapeutic promise and persisting risks
RJ Perry, GI Shulman - Journal of Biological Chemistry, 2020 - ASBMB
In a healthy person, the kidney filters nearly 200 g of glucose per day, almost all of which is
reabsorbed. The primary transporter responsible for renal glucose reabsorption is sodium …
reabsorbed. The primary transporter responsible for renal glucose reabsorption is sodium …
Systematic review of the impact of HbA1c on outcomes following surgery in patients with diabetes mellitus
Background & aims Diabetes is a significant risk factor for surgical complications and also
increases the prevalence of comorbidities, thereby increasing surgical risk. The aim of this …
increases the prevalence of comorbidities, thereby increasing surgical risk. The aim of this …
Effect of A1C and glucose on postoperative mortality in noncardiac and cardiac surgeries
W van den Boom, RA Schroeder, MW Manning… - Diabetes …, 2018 - Am Diabetes Assoc
OBJECTIVE Hemoglobin A1c (A1C) is used in assessment of patients for elective surgeries
because hyperglycemia increases risk of adverse events. However, the interplay of A1C …
because hyperglycemia increases risk of adverse events. However, the interplay of A1C …
Association between type 2 diabetes and all-cause hospitalization and mortality in the UK general heart failure population: stratification by diabetic glycemic control …
CA Lawson, PW Jones, L Teece, SB Dunbar… - JACC: Heart Failure, 2018 - jacc.org
Objectives: This study sought to investigate in the general heart failure (HF) population,
whether the associations between type 2 diabetes (T2D) and risk of hospitalization and …
whether the associations between type 2 diabetes (T2D) and risk of hospitalization and …
[HTML][HTML] Impact of preoperative glycometabolic status on outcomes in cardiac surgery: Systematic review and meta-analysis
C Corazzari, M Matteucci, M Kołodziejczak… - The Journal of Thoracic …, 2022 - Elsevier
Background Historically, impaired glucose metabolism has been associated with early and
late complicated clinical outcomes after cardiac surgery; however, such a condition is not …
late complicated clinical outcomes after cardiac surgery; however, such a condition is not …
[HTML][HTML] Low HbA1c and increased mortality risk-is frailty a confounding factor?
AH Abdelhafiz, AJ Sinclair - Aging and disease, 2015 - ncbi.nlm.nih.gov
Diabetes mellitus is increasingly becoming an older person disease due to the increased
survival and aging of the population. Previous studies which showed benefits of tight …
survival and aging of the population. Previous studies which showed benefits of tight …
The effect of frailty should be considered in the management plan of older people with Type 2 diabetes
AH Abdelhafiz, L Koay, AJ Sinclair - Future science OA, 2016 - Taylor & Francis
The prevalence of diabetes is increasing especially in older age due to increased life
expectancy. In old age, diabetes is associated with high comorbidity burden and increased …
expectancy. In old age, diabetes is associated with high comorbidity burden and increased …
Hemoglobin A1c and Cardiovascular Outcomes Following Percutaneous Coronary Intervention: Insights From a Large Single-Center Registry
Objectives The aim of this study was to evaluate post–percutaneous coronary intervention
(PCI) outcomes in relation to pre-procedural glycated hemoglobin (HbA1c) levels from a …
(PCI) outcomes in relation to pre-procedural glycated hemoglobin (HbA1c) levels from a …
The association of glycated hemoglobin A1c with coronary artery disease, myocardial infarction, and severity of coronary lesions
Y Wei, W Li, H Luan, G Tuerhongjiang… - Journal of …, 2023 - journals.sagepub.com
Glycated hemoglobin A1c (HbA1c) has been recognized as a predictor of cardiovascular
events. However, the relationship between HbA1c and coronary artery disease (CAD) in the …
events. However, the relationship between HbA1c and coronary artery disease (CAD) in the …
[HTML][HTML] Improving the accuracy of revised cardiac risk index with HbA1C: Hemoglobin ratio (HH ratio)–A retrospective cohort study
Background The current Lee's Revised cardiac risk index (RCRI) was created in 1999.
Validation studies have found RCRI to be only moderately discriminant. The “Diabetes …
Validation studies have found RCRI to be only moderately discriminant. The “Diabetes …