Immunomodulatory mechanisms of mesenchymal stem cells and their potential clinical applications
Y Huang, Q Wu, PKH Tam - International Journal of Molecular Sciences, 2022 - mdpi.com
Mesenchymal stem cells (MSCs) are multipotent stem cells with the capacity of self-renewal,
homing, and low immunogenicity. These distinct biological characteristics have already …
homing, and low immunogenicity. These distinct biological characteristics have already …
Mesenchymal stem cells and immunomodulation: current status and future prospects
F Gao, SM Chiu, DAL Motan, Z Zhang, L Chen… - Cell death & …, 2016 - nature.com
The unique immunomodulatory properties of mesenchymal stem cells (MSCs) make them
an invaluable cell type for the repair of tissue/organ damage caused by chronic inflammation …
an invaluable cell type for the repair of tissue/organ damage caused by chronic inflammation …
Trends in mesenchymal stem cell clinical trials 2004-2018: Is efficacy optimal in a narrow dose range?
M Kabat, I Bobkov, S Kumar… - Stem cells translational …, 2020 - academic.oup.com
The number of clinical trials using mesenchymal stem cells (MSCs) has increased since
2008, but this trend slowed in the past several years and dropped precipitously in 2018 …
2008, but this trend slowed in the past several years and dropped precipitously in 2018 …
Human mesenchymal stem cells (MSCs) for treatment towards immune-and inflammation-mediated diseases: review of current clinical trials
LT Wang, CH Ting, ML Yen, KJ Liu, HK Sytwu… - Journal of biomedical …, 2016 - Springer
Human mesenchymal stem cells (MSCs) are multilineage somatic progenitor/stem cells that
have been shown to possess immunomodulatory properties in recent years. Initially met with …
have been shown to possess immunomodulatory properties in recent years. Initially met with …
Safe ty of cell therapy with mesenchymal stromal cells (safecell): A systematic review and meta-analysis of clinical trials
Background Mesenchymal stromal cells (MSCs,“adult stem cells”) have been widely used
experimentally in a variety of clinical contexts. There is interest in using these cells in critical …
experimentally in a variety of clinical contexts. There is interest in using these cells in critical …
Recent progress of stem cell therapy in cancer treatment: molecular mechanisms and potential applications
The insufficient and unspecific target of traditional therapeutic approaches in cancer
treatment often leads to therapy resistance and cancer recurrence. Over the past decades …
treatment often leads to therapy resistance and cancer recurrence. Over the past decades …
Mesenchymal stromal cells for enhancing hematopoietic engraftment and treatment of graft-versus-host disease, hemorrhages and acute respiratory distress …
O Ringdén, G Moll, B Gustafsson… - Frontiers in …, 2022 - frontiersin.org
Mesenchymal stromal cells (MSCs) possess profound immunomodulatory and regenerative
properties that are of clinical use in numerous clinical indications with unmet medical need …
properties that are of clinical use in numerous clinical indications with unmet medical need …
Mesenchymal stem cells in tissue repair
AM DiMarino, AI Caplan, TL Bonfield - Frontiers in immunology, 2013 - frontiersin.org
The advent of mesenchymal stem cell (MSC)-based therapies for clinical therapeutics has
been an exciting and new innovation for the treatment of a variety of diseases associated …
been an exciting and new innovation for the treatment of a variety of diseases associated …
Mesenchymal stem or stromal cells: a review of clinical applications and manufacturing practices
Mesenchymal stem cells (MSC s) have recently generated great interest in the fields of
regenerative medicine and immunotherapy due to their unique biologic properties. In this …
regenerative medicine and immunotherapy due to their unique biologic properties. In this …
Advances in mesenchymal stem cell therapy for immune and inflammatory diseases: Use of cell-free products and human pluripotent stem cell-derived mesenchymal …
LT Wang, KJ Liu, HK Sytwu, ML Yen… - Stem cells translational …, 2021 - academic.oup.com
Mesenchymal stem cell therapy (MSCT) for immune and inflammatory diseases continues to
be popular based on progressive accumulation of preclinical mechanistic evidence. This …
be popular based on progressive accumulation of preclinical mechanistic evidence. This …