The most common forms of acquired epilepsies arise following acute brain insults such as
traumatic brain injury, stroke, or central nervous system infections. Treatment is effective for …

Ischemic stroke is a devastating disease with a complex pathophysiology. Animal modeling
of ischemic stroke serves as an indispensable tool first to investigate mechanisms of …

Abstract Purpose of Review In this review, we summarize the recent literature regarding the
incidence and treatment of seizures arising after ischemic and hemorrhagic strokes …

Stroke is a major contributor to death and disability worldwide. Prior to modern therapy, post-
stroke mortality was approximately 10% in the acute period, with nearly one-half of the …

Continuous electroencephalographic monitoring in critically ill patients has improved
detection of nonconvulsive seizures and periodic discharges, but when and how …

Neuronal excitotoxicity induced by aberrant excitation of glutamatergic receptors contributes
to brain damage in stroke. Here we show that tau-deficient (tau−/−) mice are profoundly …

Because of recent technical advances, it is now possible to record and monitor the
continuous digital electroencephalogram (EEG) of many critically ill patients simultaneously …

There is physiologic coupling of EEG morphology, frequencies, and amplitudes with
cerebral blood flow. Intraoperative continuous electroencephalographic monitoring (CEEG) …

Objective Delayed cerebral ischemia (DCI) is a common, disabling complication of
subarachnoid hemorrhage (SAH). Preventing DCI is a key focus of neurocritical care, but …

To get insight into the mechanisms that may lead to progression of temporal lobe epilepsy,
we investigated gene expression during epileptogenesis in the rat. RNA was obtained from …