Polyploidy has been hypothesized to be both an evolutionary dead-end and a source for
evolutionary innovation and species diversification. Although polyploid organisms …

Polyploidy, or the duplication of entire genomes, has been observed in prokaryotic and
eukaryotic organisms, and in somatic and germ cells. The consequences of polyploidization …

Although it is widely believed that early vertebrate evolution was shaped by ancient whole-
genome duplications, the number, timing and mechanism of these events remain elusive …

Insulin-like growth factors (IGFs) are key growth-promoting peptides that act as both
endocrine hormones and autocrine/paracrine growth factors. In the bloodstream and in local …

Ancient polyploidization events have had a lasting impact on vertebrate genome structure,
organization and function. Some key questions regarding the number of ancient …

Polyploidy, resulting from the duplication of the entire genome of an organism or cell, greatly
affects genes and genomes, cells and tissues, organisms, and even entire ecosystems …

Polyploidy, defined as the coexistence of three or more complete sets of chromosomes in an
organism's cells, is considered as a pivotal moving force in the evolutionary history of …

Whole-genome duplication (WGD) is characteristic of almost all fundamental lineages of
land plants. Unfortunately, the timings of WGD events are loosely constrained and …

Most land plants are now known to be ancient polyploids that have rediploidized.
Diploidization involves many changes in genome organization that ultimately restore …

Polyploidy or whole-genome duplication (WGD) is a major event that drastically reshapes
genome architecture and is often assumed to be causally associated with organismal …