In spite of billions of dollars expended on cancer research every year, the incidence rate and
the mortality rate due to this widespread disease has increased drastically over the last few …

Cancer is characterised by uncontrolled cell division and abnormal cell growth, which is
largely caused by a variety of gene mutations. There are continuous efforts being made to …

Honokiol (HNK) is a natural polyphenolic compound extracted from the bark and leaves of
Magnolia grandiflora. It has been traditionally used as a medicinal compound to treat …

Simple Summary The Notch signaling pathway regulates cell proliferation, apoptosis, stem
cell self-renewal, and differentiation in a context-dependent fashion both during embryonic …

Oral dichloroacetate sodium (DCA) has been investigated as a novel metabolic therapy for
various cancers since 2007, based on data from Bonnet et al that DCA can trigger apoptosis …

Background and purpose: Primary and metastatic breast cancers still represent an unmet
clinical need for improved chemotherapy and hormone therapy. Considerable attention has …

Cancer cells hijack autophagy pathway to evade anti-cancer therapeutics. Many molecular
signaling pathways associated with drug-resistance converge on autophagy induction …

The aim of the present study was to discuss the effects and underlying mechanisms of
honokiol (HNK) and/or curcumin (CUR) in sensitization of multidrug‑resistant human lung …

Colorectal cancer (CRC) is the second leading cause of cancer death. Hence, there is a
great need to explore new efficacious drugs for the treatment of CRC. Honokiol (HNK), a …

Colorectal cancer is essentially an environmental and genetic disease featured by
uncontrolled cell growth and the capability to invade other parts of the body by forming …