Oxidative stress and antioxidants in uterine fibroids: pathophysiology and clinical implications

A AlAshqar, B Lulseged, A Mason-Otey, J Liang… - Antioxidants, 2023 - mdpi.com
In the last few decades, our understanding of the complex pathobiology of uterine fibroid
development has grown. While previously believed to be a purely neoplastic entity, we now …

Adipocyte coculture induces a pro-inflammatory, fibrotic, angiogenic, and proliferative microenvironment in uterine leiomyoma cells

S Afrin, M El Sabah, A Manzoor… - … et Biophysica Acta (BBA …, 2023 - Elsevier
Objective Obesity and its consequences are among the biggest challenges facing the
healthcare system. Uterine leiomyomas are the most common gynecologic tumors. The risk …

Relationship Among Surgical Fibroid Removal, Blood Pressure, and Biomarkers of Renin–Angiotensin–Aldosterone System Activation

GW Kirschen, L Yanek, M Borahay - Reproductive Sciences, 2023 - Springer
Fibroids are common benign neoplasms in women and have recently been associated with
cardiometabolic risk factors including hypertension. The objective of this study is to …

Common Beverage Consumption and Benign Gynecological Conditions

R Michel, D Hazimeh, EE Saad, SL Olson… - Beverages, 2024 - mdpi.com
The purpose of this article is to review the effects of four commonly consumed beverage
types—sugar-sweetened beverages (SSBs), caffeinated beverages, green tea, and alcohol …

Leptin induces leiomyoma cell proliferation and extracellular matrix deposition via JAK2/STAT3 and MAPK/ERK pathways

L Reschke, S Afrin, M El Sabah, N Charewycz… - F&S Science, 2022 - Elsevier
Objective To investigate the molecular effects of leptin on uterine leiomyoma cells. Design
Experimental study using in vitro culture of immortalized human leiomyoma (HuLM) cells …

Measurement of thiol/disulfide homeostasis and ischemic modified albumin levels in patients with uterine leiomyomas

BNB Akcan, BK Yikilmaz, U Zorlu, Ö Erel… - … of Gynecology & …, 2024 - Wiley Online Library
Objective The aim is to contrast the serum levels of thiol‐disulfide homeostasis and ischemic
modified albumin between patients with leiomyoma and healthy individuals and to assess …

Obesity Contributes to Transformation of Myometrial Stem-Cell Niche to Leiomyoma via Inducing Oxidative Stress, DNA Damage, Proliferation, and Extracellular …

S Afrin, GW Kirschen, MA Borahay - Genes, 2023 - mdpi.com
Leiomyomas (fibroids) are monoclonal tumors in which myometrial stem cells (MSCs) turn
tumorigenic after mutation, abnormal methylation, or aberrant signaling. Several factors …

Obesity Contributes to Transformation of Myometrial Stem-Cell Niche to Leiomyoma via Inducing Oxidative Stress, DNA Damage, Proliferation, and Extracellular …

S Afrin, GW Kirschen, MA Borahay - 2023 - europepmc.org
Leiomyomas (fibroids) are monoclonal tumors in which myometrial stem cells (MSCs) turn
tumorigenic after mutation, abnormal methylation, or aberrant signaling. Several factors …

[HTML][HTML] Миома матки и её ассоциация с метаболическим синдромом у женщин репродуктивного возраста (обзор литературы)

НИ Бабаева, ЛВ Беленькая, ЛФ Шолохов… - Acta Biomedica …, 2022 - cyberleninka.ru
Миома матки является одним из самых распространённых гинекологических
заболеваний у женщин репродуктивного возраста, многие аспекты возникновения …

Прогнозування і генетичне обгрунтування коморбідного перебігу лейоміоми і ендометріозу

СО Вовк-Шульга - 2024 - repository.tdmu.edu.ua
У дисертації наведено узагальнення та нове вирішення наукового завдання, що
полягає в оптимізації діагностики інтрамуральної лейоміоми матки та її коморбідності з …