Many factors in the surrounding environment have been reported to influence erythrocyte
deformability. It is likely that some influences represent reversible changes in erythrocyte …

The utilizations of microfluidic chips for single RBC (red blood cell) studies have attracted
great interests in recent years to filter, trap, analyze, and release single erythrocytes for …

Alterations in the deformability of red blood cells (RBCs), occurring in hemolytic blood
disorders such as sickle cell disease (SCD), contribute to vaso-occlusion and disease …

Sickle cell disease (SCD) is a monogenic disorder characterized by recurrent episodes of
severe bone pain, multi-organ failure, and early mortality. Although medical progress over …

Red blood cell (RBC) deformability is a valuable hemorheological biomarker that can be
used to assess the clinical status and response to therapy of individuals with sickle cell …

Erythrocytes are oxygen carriers and exposed to redox cycle in oxygenation and
deoxygenation of hemoglobin. This indicates that circulating erythrocytes are vulnerable to …

The rheological properties of blood depend highly on the properties of its red blood cells:
concentration, membrane elasticity, and aggregation. These properties affect the viscosity of …

Endothelial activation and sickle red blood cell (RBC) adhesion are central to the
pathogenesis of sickle cell disease (SCD). Quantitatively, RBC‐derived extracellular …

Mechanical biomarkers distinguish health conditions through quantitative mechanical
measurements. The emergence and establishment of nanotechnology in the last decades …

Organoid models have gained importance in recent years in determining the toxic effects of
drugs in cancer studies. Organoid designs with the same standardized size and cellular …