Type 2 immunity in the skin and lungs

CA Akdis, PD Arkwright, MC Brüggen, W Busse… - Allergy, 2020 - Wiley Online Library
There has been extensive progress in understanding the cellular and molecular
mechanisms of inflammation and immune regulation in allergic diseases of the skin and …

Cellular and molecular immunologic mechanisms in patients with atopic dermatitis

T Werfel, JP Allam, T Biedermann, K Eyerich… - Journal of allergy and …, 2016 - Elsevier
Atopic dermatitis (AD) is a complex skin disease frequently associated with other diseases of
the atopic diathesis. Recent evidence supports the concept that AD can also recognize other …

The international EAACI/GA²LEN/EuroGuiDerm/APAAACI guideline for the definition, classification, diagnosis, and management of urticaria

T Zuberbier, AH Abdul Latiff, M Abuzakouk, S Aquilina… - Allergy, 2022 - Wiley Online Library
This update and revision of the international guideline for urticaria was developed following
the methods recommended by Cochrane and the Grading of Recommendations …

The EAACI/GA²LEN/EDF/WAO guideline for the definition, classification, diagnosis and management of urticaria

T Zuberbier, W Aberer, R Asero, AH Abdul Latiff… - Allergy, 2018 - Wiley Online Library
This evidence‐and consensus‐based guideline was developed following the methods
recommended by Cochrane and the Grading of Recommendations Assessment …

A basophil-neuronal axis promotes itch

F Wang, AM Trier, F Li, S Kim, Z Chen, JN Chai… - Cell, 2021 - cell.com
Itch is an evolutionarily conserved sensation that facilitates expulsion of pathogens and
noxious stimuli from the skin. However, in organ failure, cancer, and chronic inflammatory …

The EAACI/GA2LEN/EDF/WAO Guideline for the definition, classification, diagnosis, and management of urticaria: the 2013 revision and update

T Zuberbier, W Aberer, R Asero, C Bindslev‐Jensen… - Allergy, 2014 - Wiley Online Library
This guideline is the result of a systematic literature review using the 'G rading of R
ecommendations A ssessment, D evelopment and E valuation'(GRADE) methodology and a …

Thymic stromal lymphopoietin isoforms, inflammatory disorders, and cancer

G Varricchi, A Pecoraro, G Marone… - Frontiers in …, 2018 - frontiersin.org
Thymic stromal lymphopoietin (TSLP) is a pleiotropic cytokine originally isolated from a
murine thymic stromal cell line. TSLP exerts its biological effects by binding to a high-affinity …

The pathogenesis of chronic spontaneous urticaria: the role of infiltrating cells

AM Giménez-Arnau, L de Montjoye, R Asero… - The Journal of Allergy …, 2021 - Elsevier
Chronic spontaneous urticaria is characterized by a perivascular non-necrotizing cellular
infiltrate around small venules of the skin. It consists primarily of CD4 (+) lymphocytes, a …

Mechanisms of action that contribute to efficacy of omalizumab in chronic spontaneous urticaria

AP Kaplan, AM Giménez‐Arnau, SS Saini - Allergy, 2017 - Wiley Online Library
The monoclonal anti‐immunoglobulin E (IgE) antibody, omalizumab, was the first drug
approved for use in patients with chronic idiopathic/spontaneous urticaria (CIU/CSU) who …

[HTML][HTML] Th2 cytokines and atopic dermatitis

EB Brandt, U Sivaprasad - Journal of clinical & cellular immunology, 2011 - ncbi.nlm.nih.gov
Atopic dermatitis (AD), a chronic relapsing inflammatory skin disease, is increasing in
prevalence around the world. Intensive research is ongoing to understand the mechanisms …